1-苯基-3-羧基-5-吡唑啉酮的一种新合成方法  

A novel synthetic process of 1-phenyl-3-carboxy-5-pyrazolone

作　　者：孙其洪 李延泽 何云 

机构地区：[1]宿迁市永信精细化工有限公司

出　　处：《化工中间体》2012年第8期58-60,共3页

摘　　要：本文介绍了1-苯基-3-羧基-5-吡唑啉酮的一种合成方法,以乙酰基丁二酸二甲酯与苯胺重氮盐缩合、闭环,再碱性水解而得。本方法与传统方法相比因乙酰基丁二酸二甲酯的国产化及价格优势而凸现其较高的经济性,极具工业化生产价值。in this paper,a economically synthetic process of 1-phenyl-3-carboxy-5-pyrazolone is introduced,in which dimethyl acetosuccinate be condensed with the diazonium salt of aniline,then be hydrosized in alkaline medium.Due to domestication and low-price of dimethyl acetosuccinate,this process is a relatively economic procedure in contrast with the traditional process,so the process means very valuable to manufacture.

关 键 词：1-苯基-3-羧基-5-吡唑啉酮 乙酰基丁二酸二甲酯 水解 

分 类 号：TQ2[化学工程—有机化工]