单中心维持性血液透析患者睡眠质量的随访调查  

Follow-up investigation of sleep quality in maintenance hemodialysis patients in a dialysis center

作　　者：贾猛[1] 谌卫[1] 丁琳[1] 苏红[1] 吴灏[1] 郭志勇[1] 

机构地区：[1]第二军医大学附属长海医院肾内科

出　　处：《中国血液净化》2012年第4期202-205,共4页Chinese Journal of Blood Purification

摘　　要：目的通过对单中心患者睡眠质量进行纵向分析,以探讨维持性血液透析(Maintenance haemodialysis,MHD)患者睡眠障碍的动态变化规律及其影响因素。方法以本中心稳定透析大于3个月的患者为研究对象,采用匹兹堡睡眠指数(Pittsburgh sleep quality index,PSQI)量表及爱泼沃斯嗜睡量表(Epworth sleepiness scale,ESS)间隔15个月前后对本组病例的睡眠情况进行2次评估,并记录当月的血液生化相关指标以进行统计学分析。结果①第1次评估中有60例患者完成调查,其存在睡眠障碍者占60%(PSQI>5),日间嗜睡发生率为58.3%(ESS>6);②第2次评估60例患者中有55例完成调查,其存在睡眠障碍者占89%,日间嗜睡发生率为87.3%。本组病例15个月前后的比较,随着PSQI和ESS得分数值的升高,与其甲状旁腺激素(iPTH)、钙磷乘积,C反应蛋白(CRP)、血红蛋白(Hb)存在相关性,且具有统计学意义(P<0.05)。结论①随着透析龄的增加睡眠障碍存在恶化的趋势。②睡眠障碍的恶化与iPTH、钙磷乘积,CRP、Hb存在相关性。Objective Alongitudinal study was performed aimed to evaluate the dynamic change of sleep disturbances and its related factors in maintenance hemodialysis patients treated in this hemodialysis center. Methods Patients on maintenance hemodialysis for more than 3 months were recruited in this study. Sleep quality evaluation using the Pittsburgh Sleep Quality Index (PSQI) and the Epworth Sleepiness Scale (ESS) was performed twice with an interval of 15 months. Biochemical parameters were collected as well. Results ① In the 60 patients completed the sleep quality survey at the first evaluation, the incidence of sleep disturbances was 60% (PSQI > 5) and daytime sleepiness was 58.3% (ESS > 6). ② In the 60 patients, 55 completed the second sleep quality survey. Sleep disturbances accounted for 89% and daytime sleepiness 87.3% of the 55 patients. After comparing the scores of the two surveys, we found that the increase of PSQI and ESS scores was statistically correlated to the values of iPTH, calcium-phosphate product, CRP and Hb. Conclusion ① Sleep quality deteriorated along with the increase of dialysis age. ② This deterioration was related to the values of iPTH, calcium-phosphate product, CRP and Hb.

关 键 词：睡眠障碍 血液透析 生活质量 钙磷代谢 

分 类 号：R318.16[医药卫生—生物医学工程]