柠檬黄合成新工艺  

A New Synthesis Process for Tartrazine

作　　者：鄢冬茂[1] 李付刚[1] 

机构地区：[1]沈阳化工研究院有限公司,沈阳110021

出　　处：《染料与染色》2012年第3期1-3,5,共4页Dyestuffs and Coloration

摘　　要：以苯肼-4-磺酸和顺丁烯二酸二甲酯为原料,经缩合、水解和空气氧化得到中间体1-(4'-磺酸基苯基)-3-羧基-5-吡唑啉酮,然后与对氨基苯磺酸的重氮盐偶合而得柠檬黄。对合成的1-(4'-磺酸基苯基)-3-羧基-5-吡唑啉酮结构进行了表征,对反应机理进行了讨论。产品柠檬黄经检测符合GB 4481.1-2010要求。1-(4′-Sulfophenyl)-3-carboxy-5-pyrazolone was synthesized from 4-sulfophenylhydrazine and dimethyl maleate by condensation,hydrolysis and air oxidation reaction;and then,tartrazine was obtained by coupling reaction of 1-(4′-sulfophenyl)-3-carboxy-5-pyrazolone and diazonium salt of p-aminobenzene sulfonic acid.The structure of 1-(4′-sulfophenyl)-3-carboxy-5-pyrazolone was characterized and reaction mechanism of it was discussed.Product tartrazine was qualified to GB 4481.1-2010.

关 键 词：柠檬黄 1-(4 -磺酸基苯基)-3-羧基-5-吡唑啉酮 顺丁烯二酸二甲酯 空气氧化 

分 类 号：TQ613[化学工程—精细化工]