2318株结核分枝杆菌耐多药性分析  

Analysis of 2318 Mycobacterium tuberculosis resistant to multiple drugs

作　　者：骆科文[1] 刘隆平[1] 张庭梅[1] 唐发琴[1] 王燕[1] 陈红梅[1] 

机构地区：[1]贵阳市肺科医院检验科,550006

出　　处：《中华临床医师杂志（电子版）》2010年第7期928-930,共3页Chinese Journal of Clinicians(Electronic Edition)

基　　金：上海市结核病(肺)重点实验室开放基金(2007-07)

摘　　要：目的探讨贵阳市肺科医院住院结核病患者中的耐药情况,为临床诊断和治疗耐多药结核病提供可靠的科学依据。方法对2004年1月至2009年8月住院患者的临床分离株进行菌型鉴定后,进行药物敏感性试验,分析不同类型结核病患者的耐药情况。结果 2318株结核分枝杆菌耐多药率为23.8%,初始耐多药率为12.1%,获得性耐多药率为63.8%。结论目前结核病患者耐药率较高,应尽快加强耐药结核病患者的防治工作,减少和避免耐多药结核病患者的产生。Objective To explore our hospital situation in the drug resistance of tuberculosis(TB) patients for clinical diagnosis and treatment(MDR-TB),the purpose was to provide a reliable scientific evidence.Methods The clinical isolates serotype of hospitalized patients during was identified,conducted drug susceptibility tests and analyzed different types of tuberculosis drug resistance from January 2004 to August 2009.Results The rate of 2318 multi-drug resistant Mycobacterium tuberculosis was 23.8%,the initial multi-drug resistant rate was 12.1% and acquired multidrug resistance rate was 63.8% .Conclusions In our hospital,high rates of TB drug resistance,drug-resistant TB patients as soon as possible to strengthen prevention and control,reduce and prevent the emergence resistant TB patients.

关 键 词：分枝杆菌 结核 抗药性 多种 细菌 微生物敏感性试验 

分 类 号：R446.5[医药卫生—诊断学]