镍钛合金表面溶胶-凝胶TiO_2薄膜的低温制备与固定牛血清白蛋白分子  

Low-temperature Preparation of Sol-gel TiO_2 Film on NiTi Alloy and Immobilization of Bovine Serum Albumin

作　　者：董兵辉[1] 吴锋[2] 纪元[1] 付涛[1] 

机构地区：[1]西安交通大学生命科学与技术学院,西安710049 [2]西安交通大学医学院,西安710061

出　　处：《生物医学工程研究》2012年第3期161-164,168,共5页Journal Of Biomedical Engineering Research

基　　金：陕西省科技计划项目(2007K06-08);中央高校基本科研业务费专项资金资助项目(xjj2011096);国家自然科学基金资助项目(50901058)

摘　　要：采用溶胶-凝胶法和蒸汽处理,在经过双氧水粗化预处理的镍钛合金表面制备了无裂纹的TiO2薄膜。X射线衍射表明该薄膜由纳米晶粒的锐钛矿TiO2组成,X射线光电子能谱分析表明试样表面的镍含量大大降低。动电位极化和亲水性测试表明,TiO2薄膜改善了镍钛合金的耐蚀性和亲水性。通过结合3-氨丙基三乙氧基硅烷(APTES)的偶联作用,在TiO2涂层的镍钛合金表面固定了牛血清白蛋白(BSA)分子。Crack-free sol-gel titania film was prepared on the H2O2 pretreated NiTi alloy by a steam treatment.X-ray diffraction showed that the titania film was composed of nanocrystalline anatase.X-ray photoelectron spectroscopy result indicated that the Ni content at the sample surface was markedly reduced.The potentiodynamic polarization and contact angle tests showed that the TiO2 coating improved corrosion resistance and hydrophilicity of the NiTi alloy.Bovine serum albumin(BSA) molecules are immobilized on the titania film via the grafting of 3-aminopropyl-triethoxy-silane(APTES) as a coupling agent.

关 键 词：镍钛合金 TIO2 溶胶-凝胶 腐蚀 牛血清白蛋白 

分 类 号：R318.08[医药卫生—生物医学工程]