参麦注射液对慢性收缩性心力衰竭患者心功能及BNP的影响  

Influence of Shenmai Injection on Chronic Contractive Heart Failure Patients' Heart Function and BNP

作　　者：黄世恩[1] 黄琪[1] 姚强[1] 裴德安[1] 

机构地区：[1]浙江省中西医结合医院,杭州310003

出　　处：《浙江中医药大学学报》2011年第5期718-719,共2页Journal of Zhejiang Chinese Medical University

摘　　要：[目的]观察参麦注射液对慢性收缩性心力衰竭患者心功能及B型尿钠肽(BNP)的影响。[方法]将2008年6月至2010年10月间我院收治的120例慢性收缩期心力衰竭患者随机分为治疗组和对照组各60例。对照组给予吸氧、洋地黄、利尿剂、血管紧张素转换酶抑制剂、硝酸酯制剂治疗。治疗组在对照组基础上静脉滴注参麦注射液50mL/d,连续14d为1个疗程。观察两组治疗前后心功能,左室射血分数及血浆BNP变化。[结果]治疗组总有效率明显高于对照组,两组比较差异有统计学意义(P<0.05)。治疗组左室射血分数升高及血浆BNP下降较对照组更明显(P<0.05)。[结论]参麦注射液可改善慢性收缩性心力衰竭患者心功能,提高左室射血分数,降低血浆BNP水平。[Objective]To observe the influence of Shenmai injection on contractive heart failure patients' heart function and BNP.[Method] RandomLy divide 120 cases into treatment and control groups with 60 in each one;the control group takes oxygen,foreign rehmannia,diuretics, ACE inhibitor and nitric ether preparation;the treatment one added with intravenous drip of Shenmai injection;observe both groups' heart function, left ventricle ejection score and plasma BNP.[Result]In control group,total effective rate was 88.3%;and 98.3%for treatment group;there's statistical difference between them.[Conclusion]Shenmai injection can improve chronic contractive heart failure patients' heart function,left ventricle ejection score and reduce plasma BNP level.

关 键 词：慢性心力衰竭 收缩期 参麦注射液 射血分数 BNP 

分 类 号：R25[医药卫生—中医内科学]