模拟L_(4,5)椎间盘脱出前路植入两种椎间融合器压缩应力应变的分析  

Analyzing Compression Stress-strain by Analoging Implanting Two Interbody Fusion through L_(4,5) Disc Prolapse Anterior

作　　者：吴丹凯[1] 李新颖[1] 李鹏[2] 

机构地区：[1]吉林大学中日联谊医院,长春市130031 [2]吉林大学南岭校区工程力学系,长春130022

出　　处：《生物医学工程研究》2012年第4期245-249,共5页Journal Of Biomedical Engineering Research

摘　　要：以应变电测量的方法研究二种椎间融合器植入L4,5椎间隙后,相邻节段各测点的应变、应力分布规律,对比分析两种椎间融合器植入L4,5椎间隙后对相邻节段应力、应变的影响。取3月龄,体重90～100kg小牛腰椎(L2,5)标本15个,15个标本随机分成正常对照组5个、L4,5椎间盘摘除植入异种骨园柱形椎间融合器组5个、L4,5椎间盘摘除植入异种骨扁方形椎间融合器组5个。分别在每个标本L4,5间隙相邻节段(前面和后面)不同部位粘贴电阻应变片,在压缩状态下测量各组标本各测点的应变值。植异种骨园柱形椎间融合器和植异种骨扁方形柱椎间融合器组各测点应力大于正常对照组(P<0.05),植异种骨园柱形椎间融合器各测点应变、应力值大于植异种骨扁方形椎间融合器组(P<0.05)。椎间盘摘除椎间融合器植入后,在压应力作用下,相邻节段发生了变化,椎体间融合器植入后,对限制相邻节段应力变化,起了较大作用,扁方形椎间融合器效果更好。椎体间融合器植入后,相邻节段应力发生变化是引起邻近节段退变的重要原因。To research the straining、stressing distribution law of each measuring point of adjacent segment through implanting two kinds of inter-vertebral fusion cage into L4,5 inter-vertebral space in strain electrical measurement method,we could comparatively analyze the influence to the stress and strain of adjacent segments after implanting two inter-body fusion into L4,5 intervertebral space.15 specimens of 3 months old 、body weight 90~100kg calf lumbar vertebrae(L2,5) were token,then randomly divided into 5 normal control group 、5 L4,5 inter-vertebral disc implantation of xenogeneic bone cylindrical interbody fusion device group and 5 L4,5 inter-vertebral disc implantation of xenogeneic bone flat square inter-vertebral fusion device group.After resistance strain gauges being pasted in different parts of adjacent segments of each specimen L4,5 gap(front and rear),we measured all straining value of each group specimen measuring point in a compressed state.The value of stress from the group of implanting xenograft bone cylindrical inter-body fusion and the group of implanting xenograft bone flat square column inter-body fusion were greater than that of normal control group(P<0.05).The straining、 stressing value from the group of implanting xenograft bone cylindrical inter-body fusion device were greater than the group of implanting xenograft bone flat square intervertebral fusion device(P<0.05).After implanting inter-vertebral disc inter-vertebral fusion device,under compressive stressing,the value of adjacent segment changed.The implantation of inter-vertebral fusion device has played a great limited role in variation of adjacent segment stress.After implanting inter-body fusion,the variation of adjacent segment stress is an important reason to the degeneration of adjacent segments.

关 键 词：腰椎间盘脱出 植异种骨椎间融合器 压缩 应变电测量 相邻节段 退变分析 

分 类 号：R687.3[医药卫生—骨科学]