孕中晚期胎儿足长评估孕周及骨骼系统发育  

Value of Fetal Foot Length in Evaluating Gestational Weeks and Skeletal System Growth in Mid-and Late-Gestation

作　　者：钟静[1] 尹家保[1] 吕瑾玉[1] 周素芬[1] 解芸竹[1] 谢满英[1] 杨浩[1] 余岚[1] 

机构地区：[1]湖北医药学院附属襄阳医院超声影像科,湖北襄阳441000

出　　处：《湖北医药学院学报》2013年第2期136-138,142,共4页Journal of Hubei University of Medicine

基　　金：湖北省襄阳市科技基金项目(2011-5)

摘　　要：目的:探讨孕中晚期胎儿足长的超声测量方法及对孕周和骨骼系统发育的评估价值。方法:超声测量正常组500例孕18～40周胎儿股骨长(femur length,FL)及足长,换算足长/股骨长值,评定其正常值范围;研究组20例疑似股骨长与临床孕周不符的胎儿,超声测定足长、足长/股骨长值后评估孕周及骨骼发育情况。结果:正常组胎儿足长与临床孕周呈高度相关性(r=0.985,P<0.01);而足长/股骨长值与孕周无明显相关性(P>0.05);研究组足长/股骨长低于正常组,差异有统计学意义(P<0.05)。足长/股骨长=0.95～1.0胎儿骨骼系统发育基本正常;足长/股骨长=0.8～0.95多为胎儿宫内发育迟缓;足长/股骨长<0.80,提示胎儿染色体异常和骨骼系统发育不良。结论:胎儿足长/股骨长值不受孕周影响,而足长与孕周正相关,可准确评估孕周,筛查胎儿染色体及骨骼发育异常。Objective To investigate the ultrasound method for determination of fetal foot length and value of foot length in evaluating the gestational weeks and skeletal system growth.Methods The lengths of femurs and feet in 500 cases of normal 18~40 weeks fetuses were determined with ultrasound,and the value of feet length versus femur length were calculated and its normal range were evaluated.Twenty 20 fetuses suspected of femur length not conforming to gestational weeks were determined with ultrasound,then the value of foot length and foot length versus femur length were calculated to evaluate gestational weeks and skeletal system growth.Results The foot length and gestational weeks were highly correlated in normal fetuses(r=0.985,P<0.01),while there was no significant correlation with gestational weeks(P>0.05).The value of foot length versus femur length in observed group was significantly lower than that of normal group(P<0.05).The data analysis demonstrated that the normal range of foot length versus femur length was 0.95 to 1.0,the fetuses were most hypoevolutism when the value of foot length versus femur length was 0.8 to 0.95,the fetuses were chromosomal abnormality and dysplasia of skeletal systems when the value of foot length versus femur length was lower than 0.8.Conclusion Not only the value of foot length versus femur length but also the foot length was positively correlated with gestational weeks,which could be used for accurately evaluating gestational weeks and then screening chromosomal abnormality and dysplasia of skeletal systems.

关 键 词：超声 胎儿 足长 孕周 骨骼系统 

分 类 号：R714.5[医药卫生—妇产科学]