间歇性递增式常压低氧暴露训练对高原习服效果的研究  

Effects of intermittent and progressive normobaric hypoxic training on altitude acclimatization

作　　者：杨军[1] 俞梦孙[1] 曹征涛[1] 吴峰[1] 张宏金[1] 王海涛[1] 王彬华[1] 杨海平[1] 

机构地区：[1]空军航空医学研究所,北京100142

出　　处：《中华航空航天医学杂志》2012年第3期161-164,封2,共5页Chinese Journal of Aerospace Medicine

摘　　要：目的 探讨利用间歇性递增式常压低氧舱低氧暴露训练获得高原习服的效果. 方法 4名青年男性志愿者为训练组,对照组4人为健康男性工作人员.训练组用常压低氧舱进行连续10 d的间歇性、高度递增式低氧暴露训练:1次/d、210min/次,从3000m递增至4500m.用常压低氧舱监控系统监测训练中环境物理参数和受试者生理参数；用床垫式睡眠监测系统监测受试者夜间睡眠.比较训练前后相同高度时的血氧饱和度值.对照组不进行上述训练.训练组低氧训练结束后与对照组同时急进3800m高原,比较两组急进高原后的动脉血氧饱和度值. 结果 ①10 d低氧训练后,在模拟3600 m的高度,训练组的动脉血氧饱和度为(86.7±1.7)％,显著高于训练前的基线值(83.7±3.3)％(t=3.66,P＜0.05).②训练中受试者无不良反应,对夜间睡眠无影响.③急进3800m高原后,训练组的血氧饱和度为(90.7±1.2)％,显著高于对照组的(84.8±2.0)％(t=10.95,P＜0.01).结论 常压低氧舱间歇性递增式低氧训练方法,具有显著的高原预习服效果,方案安全,可满足高原作业的生理学要求.Objective Altitude acclimatization allows the personnel who rushed to high altitude with the decreased sensitivity to altitude illness.The purpose of this study is to evaluate the effects of intermittent and progressive normobaric hypoxic training on altitude acclimatization.Methods Eight healthy volunteers were randomly and averagely divided into training group (exposure group) and control group.The normobaric chamber was utilized for the intermittent and progressive normobaric hypoxic training.Volunteers of training group ascended to the simulated high altitude in the chamber 210 min a day for 10 days,and the altitude was progressively varied from 3000 m to 4500 m while control group was not exposed to hypoxic environment.Physical and physiological parameters were monitored and recorded by YB-88BX monitoring system during hypoxic exposure training.Arterial oxygen saturation (SaO2) was compared before and after intermittent hypoxic exposure.After completing the training,8 volunteers immediately rushed to the 3800 m plateau.The oxygen saturation value was compared between two groups.Results ① Compared with the value before training,mean oxygen saturation of training group was significantly increased [(86.7 ± 1.7)％ vs.(83.7± 3.3)％,t=3.66,P＜0.05] at 3600 m simulated altitude by 10-day training.② The training had no side effects on volunteers.③ After rushed to 3800 m plateau,the training group showed significantly higher oxygen saturation value than that of control group [(90.7 ± 1.2)％ vs.(84.8 ±2.0) ％,t=10.95,P＜0.01].Conclusions The intermittent and progressive normobaric hypoxic training is safe and effective on altitude acclimatization.The training can meet the physiological requirements of safe operation at altitude of 3800 m.

关 键 词：缺氧 高海拔 环境暴露 习服 

分 类 号：R85[医药卫生—航空、航天与航海医学]