ω-3鱼油脂肪乳在急性呼吸窘迫综合征中的应用  

Efficacy of ω-3 fish oil emulsion in patients with acute respiratory distress syndrome

作　　者：郭端[1] 贾超[1] 许治华[1] 

机构地区：[1]绵阳市中心医院重症医学科,四川绵阳621000

出　　处：《四川医学》2012年第11期1946-1947,共2页Sichuan Medical Journal

摘　　要：目的观察ω-3鱼油脂肪乳对有创机械通气的急性呼吸窘迫综合征(ARDS)患者的呼吸状况和临床预后的影响。方法将ARDS患者随机分为研究组和对照组,对照组采用常规治疗,研究组在常规治疗基础上加用ω-3鱼油脂肪乳剂,疗程7d。结果研究组与对照组比较,在氧合指数、机械通气时间、住ICU时间和病死率上差异均无统计学意义(P>0.05)。研究组应用ω-3鱼油脂肪乳剂注射液过程中未发现明显的不良反应。结论静脉使用ω-3鱼油脂肪乳对进行机械通气的ARDS患者的呼吸状况和临床预后无明显改善作用。Objective To investigate the effect of ω-3 fish oil emulsion on respiratory function and outcome in ventilated patients with acute respiratory distress syndrome(ARDS).Methods Patients were randomized into two groups,one receiving conventional therapy and the second receiving conventional therapy supplemented with ω-3 fish oil emulsion for 7 days.Results No statistical difference was found in oxygenation,the length of ventilation,length of ICU stay and mortality at 28 days.Conclusion In ventilated patients with acute respiratory distress syndrome,intravenousω-3 fish oil emulsion do not improve respiratory function and clinical outcome.

关 键 词：Ω-3鱼油脂肪乳 急性呼吸窘适综合征 机械通气 

分 类 号：R563.8[医药卫生—呼吸系统]