Graves甲亢并肝功能损害肝炎标志物的测定  

The hepatic virus markers determination in Graverse disease patients combine with hepatic function injured

作　　者：袁朝伟[1] 李健[1] 

机构地区：[1]自贡市第一人民医院内分泌科,四川自贡643000

出　　处：《四川医学》2012年第11期1962-1963,共2页Sichuan Medical Journal

摘　　要：目的测定Graves甲亢并肝功异常患者肝炎病毒学指标,探讨甲亢肝损害的可能原因。方法 GD甲亢并肝功损害患者200例,病程1～32个月,年龄19～62岁,男62例,女138例,均为初诊的未用过抗甲亢药物及其他对肝脏有损伤的药物的甲亢并肝功能损害的患者。测定肝功能,肝炎标志物(甲、乙、丙、丁、戊),自身免疫性肝病抗体,对造成肝损害的病因进行分析。结果 GD甲亢并肝功能损害的程度:轻度56.5%,中度43%,重度损害0.5%。造成肝功能损害的病因:病毒性肝炎16.5%,自身免疫性肝炎0.5%,甲亢性肝功能损害83%。结论 GD肝功损害的程度大多数为轻度、中度,GD甲亢并肝损害的病因最常见的为甲亢自身,其次为病毒性肝炎,重度损害多为自身免疫性肝炎。Objective To detect the hepatitis virus markers of Graves disease patients liver injured,and analyze the etiopathogenisis of liver injured.Methods Hepatic function,hepatitis markers,autoimmunity hepatopathy antibody were detected in 200 preliminary diagnosis Graves disease patients liver injured,male 62,female 138,age from 19 to 62 years,course of disease from 1 to 32 months,and the etiopathogenisis of them all were analysed.Results The degree of the liver injured revealed that there were 113 patients(56.5%)of mild degree,86 patients(43%)of moderate degree,and 86 patients(0.5%) of severe degree,respectively;the etiopathogenisis of liver injured analysis revealed that there were 33 hepatitis patients(16.5%) in all,1 autoimmune hepatitis patients(0.5%).The remaining 116 patients(83%) were Graves hyperthyroidism.Conclusion The degree of liver injured in Graves disease patients was mostly lightly or moderate,the etiopa-thogenisis of liver injured of thease patients is mainly Graves disease itself.

关 键 词：GD甲亢 肝功能损害 肝炎标志物 测定 

分 类 号：R581.1[医药卫生—内分泌]