部分脾栓塞治疗难治性特发性血小板减少性紫癜16例临床观察  

Clinical Observation of Partial Splenic Embolization for 16 Patients with Refractory Idiopathic Thrombocytopenic Purpure

作　　者：路萍[1] 宫喜翔[1] 王永志[1] 朱桂华[1] 

机构地区：[1]玉溪市人民医院血液风湿科,云南玉溪653100

出　　处：《昆明医科大学学报》2012年第5期131-134,共3页Journal of Kunming Medical University

摘　　要：目的探讨部分脾栓塞(PSE)治疗难治性原发血小板减少性紫癜(RITP)的临床疗效.方法对16例经内科治疗无效的RITP患者行PSE术治疗后的临床资料进行回顾性分析.结果 16例RITP患者PSE术后血小板均较术前发生了显著改变.PSE治疗RITP短期有效率100%,近期总有效率87.6%,远期总有效率75.0%.结论 PSE达到了与切除脾脏相似的效果,同时保留了部分脾组织,使其免疫功能得以保存,其疗效与脾切除无显著性差异,是一种治疗RITP安全、简便的手段.Objective To observe the clinical effect of partial plenic embolization(PSE) for refractory idiopathic thrombocytopenic purpure(RITP).Method 16 patients with RITP received PSE after failure of internal medicine theray,then the effects of PSE were evaluated.Results The number of blood platlets was improved significantly after operation in all cases,the short-period effective rate of PSE was 100%,the short-term effective rate was 87.6% and the long-term effective rate was 75.0%.Conclusions PSE has similar effects to resection of the spleen,at the same time,PSE reserves a part of spleen and spleen's immunity function,its curative effects show no significant differences with splenectomy.It is a safe and simple method to treat RITP.

关 键 词：难治性特发性血小板减少性紫癜 部分性脾栓塞 治疗 

分 类 号：R554[医药卫生—血液循环系统疾病]