护理干预对AMI患者心理状态及血清中sFas水平表达影响作用的研究  

On Effects of Nursing Intervention on the Psychological Status and the Expression of Serum sFas in Patients with Acute Myocardial Infarction

作　　者：刘巍[1] 王继红[1] 

机构地区：[1]北华大学护理学院,吉林吉林132013

出　　处：《北华大学学报（自然科学版）》2012年第5期570-572,共3页Journal of Beihua University（Natural Science）

摘　　要：目的探讨护理干预对急性心肌梗死患者(AMI)心理状态及血清中sFas水平表达的影响.方法将80例AMI患者分为实验组和对照组,实验组实施护理干预;入院和出院时采用症状自评量表(SCL-90)及人血清可溶性Fas试剂盒对实验组和对照组进行调查分析及血清学检测.结果 AMI患者实验组SCL-90评分出院时较入院时的评分明显下降,躯体化、焦虑、抑郁、敌对、偏执、恐怖因子评分(P<0.05)实验组sFas表达水平明显低于对照组,差异具有统计学意义(P<0.05).结论护理干预能够明显改善AMI患者的心理状态,促进疾病的康复;实施护理干预后,AMI患者血清可溶性Fas水平明显降低,这就降低了血管平滑肌细胞的凋亡率,心血管事件的发生率也会随之减少,能够间接地反映出护理干预的有效程度.Objective This study is aimed to inquire into the impact of nursing intervention on the psychological status and the expression level of serum soluble Fas(sFas)in patients with acute myocardial infarction(AMI).Method 80 patients with AMI were divided into experiment and control groups.The patients in the experiment group were given the nursing intervention.When the patients were hospitalized and discharged,the self-rating scale,also called symptom checklist(SCL-90),and human serum sFas kit were used for the investigation and the serological testing in the patients in the experiment group and the control group.Results The scores estimated with SCL-90 in the hospitalized patients with AMI in the experimental group decreased obviously compared with those when they were discharged.The scores of somatization,anxiety,depression,hostility,paranoia,and fear factors,and the expression levels of sFas of patients in the experiment group were obviously,lower than those in the control group,and the differences were significanc in statistics(P<0.05).Conclusion The nursing intervention can significantly improve the psychological status of patients with AMI and promote the rehabilitation of the disease.After the implementation of the nursing intervention,the levels of serum sFas of the patients with AMI decreased obviously,the apoptosis rate of vascular smooth muscle cells may be reduced and the incidence of cardiovascular events may be reduced with it.This might indirectly reflect the effectiveness of the nursing intervention in it.

关 键 词：护理干预 心肌梗死 血清可溶性FAS 

分 类 号：R473.5[医药卫生—护理学]