利用彩色多普勒血流显像评价移植静脉通畅性的实验研究  

Experimental study of patency assessment in vein graft by color Doppler flow imaging

作　　者：厉泉[1] 张凯伦[2] 许莉[1] 王海燕[3] 王雪梅[1] 刘天起[1] 

机构地区：[1]山东省千佛山医院心外科,济南250014 [2]华中科技大学同济医学院附属协和医院心外科 [3]山东省千佛山医院超声科,济南250014

出　　处：《中华临床医师杂志（电子版）》2012年第21期6733-6736,共4页Chinese Journal of Clinicians(Electronic Edition)

基　　金：国家自然科学基金(30571838)

摘　　要：目的探讨血管彩色多普勒血流显像在评价搭桥术后移植静脉通畅性方面的应用价值。方法构建30例兔颈动脉旁路移植模型,术后不用抗凝药物。手术当天及术后30 d行彩色多普勒血流显像检查,检测移植静脉有无血栓及其通畅性。术后30 d,取出静脉,在手术显微镜下观察该静脉有无血栓、是否通畅。记录两种方法所得的移植静脉血栓发生率和血管通畅率,比较两种方法所得结果的不同,并计算多普勒评价血栓发生和血管通畅的准确率。结果手术当天,血管多普勒证明所有30例模型移植静脉全部通畅无血栓。术后30 d,手术显微镜下观察移植静脉血栓发生率为25/30,血管通畅率为15/30,而多普勒检测的血栓发生率为21/30(P>0.05),血管通畅率为15/30(P>0.05)。多普勒检测血栓发生的准确率为84%,血管通畅的准确率为100%。结论血管彩色多普勒血流显像在评价移植静脉通畅性方面高效、准确。Objective To investigate the diagnostic value of color Doppler flow imaging(CDFI)in patency assessment of vein graft after artery bypass grafting.Methods Animal model of carotid artery bypass grafting was constructed in thirty rabbits.After operation,the anticoagulant agent was not administered to the rabbits.Vessel CDFI was applied to prove if thrombus formed in vein graft and vessel was obstructed on the day of surgery and the 30th day.Thirty days later,vein grafts were harvested for operative microscope observation of thrombosis and patency.The thrombosis and patency rates in the vein grafts derived from these two means were recorded and contrasted.The accuracy rates of thrombosis and patency in vein grafts by CDFI were calculated.Results The CDFI showed that no thrombus and obstruction was found in all thirty vein grafts on the day of surgery.Thirty days later,thrombi were found in 25 of 30 vein grafts and obstruction in 15 of 30 vein grafts observed by operative microscope.By CDFI detection,there were thrombi in 21 of 30 vein grafts(P>0.05)and obstructions in 15 of 30 vein grafts(P>0.05).The accuracy rates of thrombosis and patency in vein grafts by CDFI were 84% and 100% respectively.Conclusions Color Doppler detection in patency assessment of vein graft is efficient and accurate.

关 键 词：冠状动脉旁路移植术 非体外循环 移植 静脉血栓形成 超声检查 多普勒 彩色 

分 类 号：R445.1[医药卫生—影像医学与核医学]