高山大戟化学成分的研究  

Study on chemical constituents of Euphorbia stracheyi Boiss

作　　者：马柱坤[1] 戴源[1] 张蓓蓓[1] 廖志新[1] 

机构地区：[1]东南大学化学化工学院制药工程系,南京210009

出　　处：《西北药学杂志》2012年第1期1-4,共4页Northwest Pharmaceutical Journal

基　　金：国家自然科学基金资助项目(编号:30770233)

摘　　要：目的对藏药高山大戟的化学成分进行研究。方法利用各种柱色谱对其成分进行分离纯化,通过波谱解析进行结构鉴定。结果从中分离得到15个化合物,分别鉴定为:正二十八烷醇(1),十七烷酸甘油酯(2),正二十六烷醇(3),β-谷甾醇(4),β-胡萝卜苷(5),正十八烷醇(6),豆甾醇(7),芹菜素(8),没食子酸(9),荭草苷(10),槲皮素-4'-O-D-半乳糖(11),甘露醇(12),蔗糖(13),槲皮素-4′-O-β-吡喃葡萄糖苷(14)和木犀草素-5-O-β-D-葡萄糖苷(15)。结论所有化合物均为首次从该种植物中分离得到。Objective To study the chemical constituents of Euphorbia stracheyi Boiss.Methods The chemical constituents were isolated and purified by various chromatographic techniques.Their structures were determined on the basis of physical properties and spectroscopic data.Results Fifteen compounds were isolated and elucidated as n-octacosanol(1),1-heptadecanoyl glycerol(2),hexacosanol(3),β-sitosterol(4),β-daucosterol(5),1-octadecanol(6),stigmasterol(7),apigenin(8),gallic acid(9),orientin(10),quercetin-4′-O-D-galactoside(11),mannitol(12),sucrose(13),quercetin-4′-O-β-glucopyranoside(14) and luteolin-5-O-β-D-glucoside(15).Conclusion All compounds were isolated from this plant for the first time.

关 键 词：大戟属 高山大戟 化学成分 

分 类 号：R284[医药卫生—中药学]