复方桂朴片中厚朴提取工艺研究  

Study on extraction technique of Magnolia of ficinalis in Compound Guipu Tablets

作　　者：江宝红[1] 黄一平[2] 刘汉清[1] 鞠建明[2] 

机构地区：[1]南京中医药大学,南京210046 [2]江苏省中医药研究院,南京210028

出　　处：《西北药学杂志》2012年第1期4-6,共3页Northwest Pharmaceutical Journal

基　　金：江苏省科技厅"科技基础实施建设计划"专项(编号:BM2008152)

摘　　要：目的优选复方桂朴片中厚朴的提取工艺。方法采用L9(34)正交实验设计及综合评分法,以厚朴酚、和厚朴酚及出膏率为检测指标,考察了不同影响因素和水平对厚朴提取工艺的影响。结果最佳提取工艺为10倍量体积分数为75%的乙醇,提取3次,每次1.5h。结论优选的提取工艺合理、稳定、可行。Objective To optimize the extraction technique of Magnolia of ficinalis in Compound Guipu Tablets.Methods Orthogonal test and synthetic mark were employed,in which magnolol,honokiol and paste rates were used as evaluation maker,for investigating the influence on extracting process of Magnolia of ficinalis by different extracting factors and levels.Results The optimized extraction conditions were extraction three times by 10 times the volume fraction of 75% ethanol,with 1.5 h each time.Conclusion The optimal extraction technique is reasonable,stable and feasible.

关 键 词：复方桂朴片 厚朴 提取工艺 

分 类 号：R286[医药卫生—中药学]