曲普瑞林治疗多囊卵巢综合征不孕的疗效观察  

Observation of Triptorelin in treatment of infertile women with polycystic ovary syndrome clinical observation

作　　者：李雅琪[1] 杨炜婷 彭俊[1] 宋致蓉 廖国芳[1] 张瑜[1] 马燕[1] 罗连英[1] 

机构地区：[1]凉山州第一人民医院妇产科,四川西昌615000

出　　处：《现代预防医学》2012年第22期5825-5826,5824,共2页Modern Preventive Medicine

摘　　要：目的观察曲普瑞林对多囊卵巢综合征不孕患者促排卵的效果。方法多囊卵巢综合征患者内分泌紊乱纠正后,实验组给予曲普瑞林+HCG治疗,对照组给予氯米芬+HCG治疗,比较两组给药后排卵时间、周期排卵率、临床妊娠率、流产率等。结果实验组用药72h内排卵率(χ2=4.39)、周期排卵率(χ2=4.71)、妊娠率(χ2=3.89)明显高于对照组(P﹤0.05),还能减少OHSS(χ2=4.32)、LUFS发生率(χ2=4.69),两组流产率相似(χ2=0.09),差异无统计学意义(P﹥0.05)。结论曲普瑞林具有较好的促排卵效果,与HCG合用更能提高排卵妊娠率。OBJECTIVE To observe triptorelin in infertile patients with polycystic ovary syndrome in ovulation induction effect.METHODS Polycystic ovary syndrome in patients with endocrine disorders after correcting,the experimental group was given triptorelin in + HCG treatment,the control group was given clomiphene + HCG treatment,were compared between the two groups after the administration of the time of ovulation,ovulation rate,clinical pregnancy rate and miscarriage rate.RESULTS The experimental group after 72 hours of ovulation rate(χ2 = 4.39),cycle ovulation rate(χ2 = 4.71),pregnancy rate(χ2 = 3.89)was higher than that of control group(P﹤0.05),but also can reduce the incidence rate of LUFS(χ2 = 4.32),OHSS(χ2 = 4.69),abortion rate of the two groups is similar(χ2 = 0.09)(P﹥0.05).CONCLUSION Triptorelin has better efficacy of ovulation induction,and HCG combination can improve ovulation pregnancy rate.

关 键 词：曲普瑞林 多囊卵巢综合征 促排卵 

分 类 号：R711.75[医药卫生—妇产科学]