曲马多预防开颅手术术后寒战的研究  

Study on the tramadol in prevention of postoperative chill of craniotomy

作　　者：肖文鑫[1] 赵崇汉[1] 陈珍爱[1] 

机构地区：[1]南方医科大学附属新会人民医院,广东江门529100

出　　处：《现代预防医学》2012年第22期6016-6017,6011,共2页Modern Preventive Medicine

摘　　要：目的探讨曲马多用于颅脑开放手术中预防寒战的效果。方法选择某院2010～2012年颅脑开放手术患者60例随机分成两组,实验组(n=30)和对照组(n=30)。手术结束前15min,实验组患者静脉注射曲马多1mg/kg及甲氧氯普安10mg,对照组患者静脉注射0.9%氯化钠5ml及甲氧氯普安10mg。观察拔除气管导管时、拔管后15min、30min、60min患者寒战发生的情况及生命体征变化情况。结果在拔除气管导管时、拔管后60min时段患者较少发生寒战(P﹥0.05);而在拔管后15min和30min时段,实验组患者寒战的发生明显少于对照组(P﹤0.05)。结论曲马多能有效预防开颅手术术后寒战的发生。OBJECTIVE To study the effect of tramadol in prevention of postoperative chill of craniotomy.METHODS 60 patients with craniotomy from 2010 to 2012 were randomly divided into test group and control group.15 minutes before operation,patients in test group were treated with intravenous tramadol 1mg/kg and motoclopramide 10mg,patients in control group were treated with intravenous 0.9% sodium chloride 5ml and motoclopramide 10mg.Incidences of chill and vital signs were monitored in all at time intervals of tracheal extubation,15min,30min and 60min after extubation.RESULTS Chill seldom happened at the beginning of extubation and after extubation 60 minutes(P﹥0.05);Chill in test group was significantly less than that in control goup after extubation 15 minutes and 30 minutes(P﹤0.05).CONCLUSION Tramadol can effectively prevent the happening of postoperative chill of craniotomy.

关 键 词：曲马多 开颅手术 寒战 

分 类 号：R614[医药卫生—麻醉学]