二维应变成像技术评价左心室构型正常高血压患者的心肌功能  

Evaluation of myocardial function in patients with essential hypertension with left ventricular normal geometry using two dimensional strain imaging

作　　者：李真真[1] 王志斌[1] 孙品[1] 聂晶[1] 李艳[1] 付秀秀[1] 张金慧[1] 

机构地区：[1]青岛大学医学院附属医院心脏超声科,266003

出　　处：《中华医学超声杂志（电子版）》2013年第1期52-58,共7页Chinese Journal of Medical Ultrasound(Electronic Edition)

摘　　要：目的应用二维应变成像检测原发性高血压左心室构型正常患者心肌应变,并探讨其临床意义。方法选择左心室构型正常的原发性高血压患者70例和健康志愿者30例(健康对照组),原发性高血压患者中左心室舒张充盈正常者(左心室舒张充盈正常组)35例,松弛性减低者(左心室松弛性减低组)35例。采集心尖四腔心切面、二腔心切面、左心室长轴切面及胸骨旁乳头肌水平左心室短轴切面的二维灰阶动态图像。应用二维应变成像测量左心室纵向、圆周、径向应变率。结果健康对照组、左心室舒张充盈正常组、左心室松弛性减低组收缩期纵向峰值应变率分别为(-1.4±0.2)s-1、(-1.4±0.2)s-1、(-1.2±0.2)s-1,组间比较差异有统计学意义(F=11.38,P=0.00),且左心室松弛性减低组与健康对照组、左心室舒张充盈正常组比较,差异均有统计学意义(q=5.68、5.92,P均<0.01)。健康对照组、左心室舒张充盈正常组、左心室松弛性减低组舒张早期纵向峰值应变率分别为(2.9±0.4)s-1、(2.6±0.3)s-1、(2.3±0.4)s-1,组间比较差异有统计学意义(F=21.51,P=0.00),且左心室舒张充盈正常组、左心室松弛性减低组与健康对照组比较,差异均有统计学意义(q=4.63、9.27,P均<0.01),左心室舒张充盈正常组与左心室松弛性减低组比较,差异有统计学意义(q=4.82,P<0.01)。健康对照组、左心室舒张充盈正常组、左心室松弛性减低组心房收缩期纵向峰值应变率分别为(1.2±0.2)s-1、(1.2±0.2)s-1、(1.4±0.2)s-1,组间比较差异有统计学意义(F=11.38,P=0.00),且左心室松弛性减低组与健康对照组、左心室舒张充盈正常组比较,差异均有统计学意义(q=5.68、5.92,P均<0.01)。健康对照组、左心室舒张充盈正常组、左心室松弛性减低组收缩期圆周峰值应变率分别为(-1.4±0.4)s-1、(-1.5±0.3)s-1、(-1.8±0.4)s-1,组间比较差异有统计学意义(F=10.66,P=0.00),且左心室松弛性减低�Objective To evaluate the value of two dimensional strain imaging in assessing left ventricular myocardium strain in patients with essential hypertension and normal left ventricular geometry.Methods Thirty normal subjects and seventy patients with essential hypertension with normal left ventricular geometry were enrolled,including 35 cases with normal filling and 35 cases with abnormal relaxation.The longitudinal strain rate curves were determined in apical 2-chamber views,4-chamber views and long-axis of left ventricle views.Radial and circumferential strain rate curves were determined in the parasternal short-axis views at the level of the papillary muscles.Results The mean peak systolic longitudinal strain rate were(-1.4±0.2) s-1,(-1.4±0.2)s-1,(-1.2±0.2)s-1 in normal control group,normal filling group and abnormal relaxation group respectively,with significant differences among the groups(F=11.38,P=0.00).The significant differences were identified in following comparisons:group normal control/normal filling with abnormal relaxation group(q=5.68,5.92,both P<0.01).The mean peak early diastolic longitudinal strain rate were(2.9±0.4)s-1,(2.6±0.3)s-1,(2.3±0.4)s-1 in normal control group,normal filling group and abnormal relaxation group respectively.There were significant differences among the groups(F=21.51,P=0.00).The significant differences were identified in following comparisons:group normal filling/abnormal relaxation group with normal control group(q=4.63,9.27,both P<0.01),normal filling group with abnormal relaxation group(q=4.82,P<0.01).The mean peak LV systolic longitudinal strain rate during atrial systole were(1.2±0.2)s-1,(1.2±0.2)s-1,(1.4±0.2)s-1 in normal control group,normal filling group and abnormal relaxation group respectively.There were significant differences among the groups(F=11.38,P=0.00).In detail,the significant differences were identified in following comparisons:group normal control/normal filling with abnormal relaxation group(q=5.68,5.92,both P<0.01).The mean peak systolic cir

关 键 词：超声心动描记术 二维应变成像 高血压 心室功能 左 心肌应变 

分 类 号：R544.1[医药卫生—心血管疾病]