磷酸肌酸钠治疗新生儿重度窒息心肌损害临床对照研究  

Controlled Clinical Research of Creatine Phosphate in the Treatment of Severe Neonatal Asphyxia Myocardial Damage

作　　者：王依[1] 陈群娣[1] 

机构地区：[1]博罗县人民医院儿科,广东博罗516100

出　　处：《黑龙江医学》2013年第7期542-543,共2页Heilongjiang Medical Journal

摘　　要：目的研究磷酸肌酸钠治疗新生儿重度窒息心肌损害的临床效果。方法将34例新生儿窒息伴重度心肌损害的新生儿随机分为治疗组及对照组,对照组采用常规治疗,治疗组加用磷酸肌酸钠治疗,对比两组临床结果差异性。结果治疗组的治疗效果(82.35%)明显优于对照组(47.06%),并且经积极治疗后治疗组患儿心肌酶谱数值均小于对照组。结论磷酸肌酸钠作为一种新型的细胞保护剂,在重度新生儿窒息伴心肌损害的治疗中加用,有助于提高治疗效果。Objective To study the clinical effect of creatine phosphate in the treatment of severe neonatal asphyxia myocardial damage.Methods 34 cases of neonatal asphyxia in neonates with severe myocardial damage were randomly divided into treatment group and control group,the control group with conventional therapy and the control group with creatine phosphate treatment.Clinical outcome differences of two groups were compared.Results The therapeutic effect of the treatment group(82.35%) was significantly higher than that of the control group(47.06%),and the myocardial enzyme was active in the treatment group.The spectral values were less than that of the control group.Conclusion The creatine phosphate sodium as a cell model agent,in the treatment of severe neonatal asphyxia with myocardial damage plus creatine,helps to improve the therapeutic effect.

关 键 词：磷酸肌酸钠 新生儿窒息 心肌损害 

分 类 号：R722.12[医药卫生—儿科]