急性心肌梗死患者血小板参数和超敏C反应蛋白测定的临床意义  

Detection of Platelet Parameters and High Sensitivity C-reactive Protein in Patients with Acute Myocardial Infarction and Their Clinical Significance

作　　者：陈伯良 陈克家[2] 

机构地区：[1]汕尾市海丰县彭湃纪念医院ICU室,广东海丰516400 [2]暨南大学附属第一医院急诊科,广东广州510630

出　　处：《黑龙江医学》2013年第7期599-600,共2页Heilongjiang Medical Journal

摘　　要：目的探讨急性心肌梗死(AMI)患者血小板参数及超敏C反应蛋白测定的临床价值。方法将46例心肌梗死患者设定为AMI组,32例健康体检者设定为对照组。对两组进行采血检测血小板4项参数,包括血小板计数、血小板平均体积、血小板体积分布宽度和大血小板比率,以及超敏C反应蛋白的水平。结果 AMI组血小板计数水平低于对照组,而血小板平均体积、血小板体积分布宽度及大血小板比率水平则高于对照组,两组比较差异均有统计学意义(P<0.01);AMI组的超敏C反应蛋白水平也明显高于对照组(P<0.01)。结论血小板参数和超敏C反应蛋白水平与急性心肌梗死的发生、发展有着密切的关系,两者均可作为急性心肌梗死发病及判断其严重程度的重要指标。Objective To investigate the clinical value of detecting platelet parameters and high sensitivity C-reactive protein(hs CRP) in patients with acute myocardial infarction(AMI).Methods The platelet four parameters,including platelet count(PLT),mean platelet volume(MPV),platelet distribution width(PDW) and platelet-large cell ratio(P-LCR) Hs-CRP were detected in 46 patients with AMI and 32 health examiners(control group).Results The levels of PLT in the AMI group were lower than that of the control group,while the levels of MPV,PDW and P-LCR in AMI group were higher than that of the control group(P < 0.01).The level of Hs-CRP in AMI group were higher than that of the control group(P < 0.01).Conclusion The levels of platelet parameters and Hs-CRP are closely correlated with the occurrence and progress of AMI.They may be used as important indexes of the attack and severity degree of AMI.

关 键 词：急性心肌梗死 血小板参数 超敏C反应蛋白(hs-CRP) 

分 类 号：R542.2[医药卫生—心血管疾病]