代谢组学应用于中药制剂各关键环节的研究概况及思考  

Review and thinking on application of metabolomics in key link of Traditional Chinese Medicine preparation

作　　者：卢君蓉[1] 何瑶[1] 傅超美[1] 胡慧玲[1] 王战国[2] 刘芳[1] 

机构地区：[1]成都中医药大学药学院 中药材标准化教育部重点实验室 中药资源系统研究与开发利用省部共建国家重点实验室培育基地,四川成都610075 [2]四川大学生命科学学院,四川成都610065

出　　处：《中药与临床》2013年第1期22-26,共5页Pharmacy and Clinics of Chinese Materia Medica

基　　金：国家自然科学基金面上项目(81073070);国家自然科学基金青年基金项目(81001638)

摘　　要：本文简述了代谢组学在中药制剂各关键环节的应用,结合课题组采用代谢组学方法开展的中药制剂相关研究,提出将代谢组学方法用于中药制剂研究和中药制剂质量全方位控制的新思路,以完善中药制剂的质量控制体系,保障中药制剂的安全有效、稳定可控。In the article, the application of metabonomics in each key link of Chinese materia medica preparation is summarized. Combined with the related research on traditional Chinese medicine preparation using metabonomics, a new idea is put forward that metabonomics could be used in research of traditional Chinese medicine preparation and comprehensive quality control of preparations, which can improve the quality control system of traditional Chinese medicine preparations and ensure the safety, effect, stability and controllability of Chinese materia medica preparation.

关 键 词：代谢组学 中药制剂 关键环节 质量控制体系 

分 类 号：R283[医药卫生—中药学]