Optimization of Smashing Tissue Extraction Technology of Schisandra chinensis Fruits by Orthogonal Test  

作　　者：Yun TANG Yan-ze LIU Ling HAN Yu-qing ZHAO 

机构地区：Shenyang Pharmaceutical University,Shenyang 110016,China[1] Institute of Medicinal Plant Development,Chinese Academy of Medical Sciences,Beijing 100193,China Bio-organic and Natural Product Laboratory,McLean Hospital/Harvard Medical School,MA 02478,USA[2] Liaoning Benxi Third Pharmaceuticals Co.,Ltd.,Benxi 117004,China[3] Shenyang Pharmaceutical University,Shenyang 110016,China Key Laboratory of Structure-Based Drug Design & Discovery,Ministry of Education,Shenyang Pharmaceutical University,Shenyang 110016,China[4]

出　　处：《Chinese Herbal Medicines》2012年第3期259-262,共4页中草药（英文版）

基　　金：E&T modern center for Natural Products of Liaoning Province of China (2008402021)

摘　　要：Objective To optimize the extract technology of active lignins from the fruits of Schisandra chinensis. Methods The content of schizandrin, gomisin A, and deoxyschizandrin were selected as standards to evaluate the efficiency of smashing tissue extraction (STE). Solid-liquid ratio, extracting times, ethanol concentration, and extracting time were investigated through orthogonal test. Results The optimized conditions for STE were ten times amount of 80% EtOH, extracting for three times, and 2 min for each time. Conclusion STE could obtain relatively higher yield, simplicity of operation, and benefit for environment protection. It could be better choice for the extraction of S. chinensis.Objective To optimize the extract technology of active lignins from the fruits of Schisandra chinensis. Methods The content of schizandrin, gomisin A, and deoxyschizandrin were selected as standards to evaluate the efficiency of smashing tissue extraction (STE). Solid-liquid ratio, extracting times, ethanol concentration, and extracting time were investigated through orthogonal test. Results The optimized conditions for STE were ten times amount of 80% EtOH, extracting for three times, and 2 min for each time. Conclusion STE could obtain relatively higher yield, simplicity of operation, and benefit for environment protection. It could be better choice for the extraction of S. chinensis.

关 键 词：DEOXYSCHIZANDRIN gomisin A orthogonal test Schisandra chinensis schizandrin smashing tissue extraction 

分 类 号：R284.1[医药卫生—中药学]