An Overview on the Progress of Chemical Constituents and Bioactivities of Plants in Urticaceae during 2000-2010  

作　　者：WANG Jian1,2,YANG Hong-xing3,TENG Yong-zhen4,YUAN Pei4,TIAN Rui4,LIAO Chun-bi5 1.College of Traditional Chinese Medicine,Chongqing Medical University,Chongqing 400016,China 2.College of Pharmacy,Chengdu University of Traditional Chinese Medicine,Chengdu 611137,China 3.Department of Anesthesiology,Daping Hospital,the Third Military Medical University,Chongqing 400042,China 4.Institute of Life Sciences,Chongqing Medical University,Chongqing 400016,China 5.Experimental Teaching Administration Center,Chongqing Medical University,Chongqing 400016,China 

出　　处：《Chinese Herbal Medicines》2011年第1期9-16,共8页中草药（英文版）

摘　　要：Urticaceae includes about 1300 species in 47 genera which largely spread in wet tropical regions,and 341 species in 25 genera are in China.Some species are used in Chinese folk medicine.So far,studies on chemistry and pharmacology of Urticaceous plants are mainly focused on nettle of Urtica L.In this review,the chemical researches on 35 new compounds and related pharmacological effects of the plants in Urticaceae reported during 2000-2010 are described.The 35 new compounds belong to the classes of lignan,secolignan,norlignan,flavonoid,alkaloid,sesquiterpenoid,triterpenoid,sterol,and sphingolipid.The main bioactivities include cytotoxic,antitumor,antimicrobial,antifungal,anti-BPH,anti-HIV,antidiabetic,hypolipidemic,5α-reductase inhibitory,hair regrowth promotion,and anti-oxidative activities.Urticaceae includes about 1300 species in 47 genera which largely spread in wet tropical regions,and 341 species in 25 genera are in China.Some species are used in Chinese folk medicine.So far,studies on chemistry and pharmacology of Urticaceous plants are mainly focused on nettle of Urtica L.In this review,the chemical researches on 35 new compounds and related pharmacological effects of the plants in Urticaceae reported during 2000-2010 are described.The 35 new compounds belong to the classes of lignan,secolignan,norlignan,flavonoid,alkaloid,sesquiterpenoid,triterpenoid,sterol,and sphingolipid.The main bioactivities include cytotoxic,antitumor,antimicrobial,antifungal,anti-BPH,anti-HIV,antidiabetic,hypolipidemic,5α-reductase inhibitory,hair regrowth promotion,and anti-oxidative activities.

关 键 词：BIOACTIVITIES chemical constituents nettle Urtica L. URTICACEAE 

分 类 号：R284[医药卫生—中药学]