RP-HPLC Determination of 1,3-Dideoxygalactonojirimycin in Bombycis Faeces  

作　　者：QI Hui,ZHAO Hui,DING Zhen-ying,ZHU Yuan-yuan Tianjin Key Laboratory of Molecular Drug Research,College of Pharmacy,Nankai University,Tianjin 300071,China 

出　　处：《Chinese Herbal Medicines》2011年第2期156-158,共3页中草药（英文版）

摘　　要：Objective To establish a simple and rapid method for the determination of 1,3-dideoxygalactonojirimycin in Bombycis Faeces,a potent glucosidase inihibitor,by HPLC.Methods A RP-HPLC method with fluorescence detection has been developed.Results The HPLC method developed in this research has a good reliability including accuracy and precision.The detection limit was less than 72 ng.Conclusion This method is sufficiently sensitive for determining 1,3-dideoxygalactonojirimycin in Bombycis Faeces and other related products.Objective To establish a simple and rapid method for the determination of 1,3-dideoxygalactonojirimycin in Bombycis Faeces,a potent glucosidase inihibitor,by HPLC.Methods A RP-HPLC method with fluorescence detection has been developed.Results The HPLC method developed in this research has a good reliability including accuracy and precision.The detection limit was less than 72 ng.Conclusion This method is sufficiently sensitive for determining 1,3-dideoxygalactonojirimycin in Bombycis Faeces and other related products.

关 键 词：Bombycis Faeces 1 3-dideoxygalactonojirimycin extraction glucosidase inhibitor RP-HPLC 

分 类 号：R446.1[医药卫生—诊断学]