正辛基缩水甘油醚的合成优化研究  

Synthesis Optimization Research on Octyl Glycidyl Ether

作　　者：刘霜[1] 唐善法[1] 刘湘[2] 岳泉[2] 陈世栋[1] 

机构地区：[1]长江大学石油工程学院,湖北荆州434023 [2]江汉石油管理局勘探开发研究院,湖北潜江433124

出　　处：《精细化工原料及中间体》2010年第6期19-22,共4页Fine Chemical Industrial Raw Materials & Intermediates

摘　　要：以正辛醇和环氧氯丙烷为原料,在四丁基溴化铵做相转移催化剂条件下,合成了正辛基缩水甘油醚。根据正交实验设计确定了最佳反应条件,通过红外光谱表征了产物的结构,并依据气相色谱流出曲线计算了产物的纯度。实验结果表明:n(辛醇):n(环氧氯丙烷)=1:1.4、反应温度为40~50℃、反应时间为4~5h时、碱的质量分数约为50%时,产物的产率最高可达91.6%,纯度可达87%以上。Octyl glycidyl ether was prepared by the reaction of n-octyl alcohol with epichlorohydrin in the presence of tetrabutyl ammonium bromide as phase-transfer catalyst. According to the orthogonal experimental design, optimal reaction conditions were determined. The structure of the product was characterized by infrared spectroscopy while the purity was calculated according to elution profile of gas chromatogram. The results showed that when n (octyl alcohol): n (epichlorohydrin) was 1:1.4, the reaction temperature was 40~50℃, the reaction time was 4~5h, the concentration of alkali was about 50%, the product got highest yield up to 91.6% and the purity was above 87%.

关 键 词：正辛基缩水甘油醚 正交实验设计 红外光谱 气相色谱 

分 类 号：TQ223.24[化学工程—有机化工]