Mg^(2+)对超速驱动后离体大鼠心脏的保护作用  

Research on the protective function of Mg^(2+) to the isolated rat heart after overdriving

作　　者：李岩[1] 颜辉[1] 

机构地区：[1]烟台师范学院体育学院,山东烟台264025

出　　处：《体育学刊》2004年第4期49-51,共3页Journal of Physical Education

摘　　要：为研究Mg2+对疲劳心脏的保护作用,以离体大鼠心脏为研究对象,采用Langendorff灌流装置对超速驱动的离体心脏施加不同浓度Mg2+的灌流液。结果表明,一定浓度的Mg2+溶液对离体心脏具有明显的保护作用,表现为心肌乳酸脱氢酶漏出减少,谷胱甘肽过氧化物酶活性增高,丙二醛含量降低,心肌组织和线粒体钙超载减轻。Taking isolated rat hearts as research objective,with the adoption of Langendorff perfusion device,Mg^(2+) perfusion solution of varied concentration is exerted on the overdriven isolated hearts for the research of the protective function of Mg^(2+) towards fatigue hearts. The results indicate that Mg^(2+) solution of certain concentration possesses tangible protective effect on isolated hearts with performances of the decrease of the transudation of myocardium LDH,the increase of the activity of GSH-PX,the decrease of the content of MDA and the alleviation of the calcium overloading in myocardium and mitochondrion.

关 键 词：镁离子 超速驱动 离体大鼠心脏 

分 类 号：G804.7[文化科学—运动人体科学]