轻度认知功能障碍患者动态脑电图的定量分析  

Analysis of Mild Cognitive Impairment in Patients with the Quantitative Dynamic EEG

作　　者：柳琳[1] 陈宇[2] 

机构地区：[1]山东中医药大学附属医院,济南250011 [2]济南市妇幼保健院,济南250001

出　　处：《生物医学工程研究》2013年第3期192-194,共3页Journal Of Biomedical Engineering Research

摘　　要：探讨轻度认知功能障碍患者动态脑电图的量化指标,为认知功能障碍早期诊断预防提供依据。选取30例轻度认知功能障碍患者和30例正常老年人作为病例组和对照组,进行MMSE测试和动态脑电图监测,比较两组观察对象α、β、和慢波功率。病例组和对照组的双侧顶枕α功率及大脑各位点的θ和δ功率差别有统计学意义(P<0.05)。病例组及对照组在睡眠2期纺锤波的时限、频率及密度差别有统计学意义(P<0.05))。脑电图α功率下降,θ和δ功率增加可以提示认知功能下降,睡眠2期纺锤波的时限、频率及密度可以作为认知功能水平脑电图测试的参考指标。To investigate the quantitative indicators of mild cognitive dysfunction in patients with EEG,to provide evidence for the prevention of early diagnosis of cognitive dysfunction.We selected 30 cases of patients with mild cognitive impairment and 30 normal elderly people as case group and control group,the MMSE test and dynamic EEG monitoring were carried on.Two groups of objects alpha,beta,and slow wave power were compared.Both cases and controls of the parieto occipital alpha power and brain all theta and delta power,there is a statistically significant difference (P<0.05).The case group and the control group have statistical significance in the sleep stage 2 spindles of time,frequency and density difference (P<0.05).

关 键 词：轻度认知功能障碍 动态脑电图 定量分析 

分 类 号：R318[医药卫生—生物医学工程]