后扩张在老年患者钙化病变PCI术中应用的临床研究  

Observation on therapeutic effects of post-dilatation for elderly patients with coronary artery calcification lesion

作　　者：董平栓[1] 陈瑞晓[1] 王红雷[1] 李志娟[1] 王可[1] 杨旭明[1] 王绍欣[1] 李转珍[1] 范喜梅[1] 杜来景[1] 

机构地区：[1]河南科技大学第一附属医院心内科,洛阳471003

出　　处：《中国医学前沿杂志（电子版）》2012年第10期59-62,共4页Chinese Journal of the Frontiers of Medical Science(Electronic Version)

基　　金：洛阳市科技攻关计划项目(1001011A-2)

摘　　要：目的观察后扩张在老年患者冠状动脉钙化病变经皮冠状动脉介入治疗(percutaneous coronary intervention,PCI)术中应用的疗效和安全性。方法选择PCI血管造影成功的老年钙化血管造影病变患者124例,随机分为后扩张组(62例)和对照组(常规置入组;62例),观察两组患者PCI术中并发症发生率及住院期间及术后1年支架内血栓、再狭窄和主要不良心脏事件(major adverse cardiac events,MACE)发生率。结果后扩张组和常规置入组患者PCI术中并发症发生率两组间比较差异无显著性(6.5%︰4.8%,P>0.05);1年时的随访结果显示,后扩张组的MACE发生率较对照组降低(4.8%︰12.9%,P<0.05);支架内血栓和支架内再狭窄发生率较常规置入组均明显减少(1.6%︰4.8%;4.4%︰14.3%,P<0.05),差异有显著性。结论在老年钙化病变患者PCI术中应用后扩张治疗安全、有效,能够降低支架内血栓、再狭窄和MACE发生率。Objective To observe the clinical therapeutic effect and security of adjunctive balloon postdilatation applying to percutaneous coronary intervention for elderly patients with coronary artery calcification lesion. Methods 124 elderly patients with coronary artery calcification lesion and successful angiograph in our hospital were randomly divided into the post-dilatation deployment group (n=62) and the control group (n=62). The complications of intraoperative and stent thrombosis, stent restenosis and major adverse cardiac events (MACE) within hospitalization and one year were observed. Results Intraoperative complications were similar between the two groups (6.5%︰4.8%, P>0.05). Stent thrombosis, stent restenosis, major adverse cardiac events were significantly lower in post-dilatation deployment group than in control group at 1 year. (1.6%︰4.8%; 4.4%︰14.3%; 4.8%︰12.9%. all P<0.05). Conclusions Routine post-dilatation approoach is safe and effective for elderly patients with coronary artery calcification lesion undergoing PCI. It was assosiated lower stent thrombosis, stent restenosis, major adverse cardiac events and improved prognosis.

关 键 词：后扩张 冠状动脉疾病 经皮冠状动脉介入治疗 钙化病变 

分 类 号：R543[医药卫生—心血管疾病]