CVI988/Rispens冷冻苗鸡胚胎免疫的免疫病理学机制  

Study on the immunopathology mechanism of embryo vaccinated with CVI 988/Rispens in chicken

作　　者：殷中琼[1] 贾仁勇[2] 蔡金元[2] 丘小燕[2] 卢明辉[2] 刘世贵[1] 

机构地区：[1]四川大学生命科学院,四川成都610064 [2]西南农业大学动科院荣昌校区,重庆荣昌402460

出　　处：《中国预防兽医学报》2004年第4期304-306,共3页Chinese Journal of Preventive Veterinary Medicine

基　　金：重庆市教育委员会重点资助项目

摘　　要：用CVI988/Rispens冷冻苗免疫 18日龄的鸡胚 ,观察淋巴器官的超微结构变化 ,揭示胚胎免疫的免疫病理学机制。结果显示 :胚胎免疫组和胚胎免疫攻毒组的淋巴细胞活性增加 ,细胞核仁数目和胞浆内线粒体数目增多 ;非免疫攻毒组的淋巴细胞感染病毒 ,引起细胞核膜和线粒体受损 ,细胞有明显的退行性变化 ,表现为细胞大小不一 ,常染色质增加 ,异染色质减少。由此可见 ,18日龄胚胎免疫对淋巴器官的早期发育具有明显的免疫促进作用 。day-old chicken embryos were vaccinated with CVI 988/Rispens,experiment revealed the immunopathology mechanism of embryo vaccinated by obsevation the ultrastructure of lympholytes cell.The results showed that embryonic vaccination with CVI 988/Rispens was obviously helpful for the activity of embryogenesis at the earlier period.Such as the activity Lympholytes,the population of nucleolus and mitochondria increased.Retrogression of lympholytes, however,was obvious in unvaccinated chickens when infected with Marek's disease virus.Such as the karyotheca and mitochondria be damaged,and the proportion of enchromation increased and the heterochromation reduced etc.

关 键 词：鸡马立克氏病 胚胎免疫 免疫病理学机制 

分 类 号：S852.4[农业科学—基础兽医学]