一种从广藿香油中快速分离纯化广藿香酮和百秋李醇的方法  

A method of rapid isolation and purification of patchouli alcohol and pogostone from patchouli oil

作　　者：李小红[1] 彭成[1] 周勤梅[1] 熊亮[1,2] 林大胜 郭力[1] 

机构地区：[1]成都中医药大学中药资源系统研究与开发利用省部共建国家重点实验室培育基地,成都611137 [2]成都华神集团股份有限公司,成都610075

出　　处：《中药与临床》2013年第6期4-6,共3页Pharmacy and Clinics of Chinese Materia Medica

基　　金：国家支撑计划重点项目(2009BAI84B00);四川省重大科研支撑项目(2012JY114)

摘　　要：目的:建立从广藿香油中快速分离高纯度广藿香酮和百秋李醇的方法。方法:利用水蒸气蒸馏法提取广藿香挥发油,分别采用碱溶酸沉法和包结物晶析法对广藿香酮和百秋李醇进行分离,并运用GC-MS法检验纯度。结果:在短时间内获得了高纯度的广藿香酮和百秋李醇。结论:所建立的方法快速、简便,为广藿香酮和百秋李醇的实际应用提供了一种思路。Objective: To establish a method of rapid isolation and purification of patchouli alcohol and pogostone from patchouli oil. Method: The oil was obtained by steam distillation. Patchouli alcohol and pogostone were isolated and purified by alkali-solution and acid-isolation and crystalline inclusion method respectively. Their structures and purities were identified by GC-MS. Result: Pachouli alcohol and pogostone with high purity was obtained in a short time. Conclusion: The established method is simple and rapid and provides an idea for the application of patchouli alcohol and pogostone.

关 键 词：广藿香油 广藿香酮 百秋李醇 分离纯化 

分 类 号：R284.2[医药卫生—中药学]