胺碘酮和美托洛尔在老年房颤患者转律后维持窦律中的疗效及不良反应比较  

Comparison of efficacy and adverse reactions between amiodarone and metoprolol in elderly patients with atrial fibrillation

作　　者：宋珂[1] 陈巧玲[1] 

机构地区：[1]蚌埠市第三人民医院老年科,蚌埠233000

出　　处：《江苏实用心电学杂志》2013年第2期591-592,595,共3页Journal of Practical Electrocardiology JS

摘　　要：目的探讨对于老年房颤患者在临床上采用美托洛尔和胺碘酮治疗的效果,并分析其所发生的不良反应。方法选取我院收治的老年房颤患者50例进行临床观察,将患者随机分为观察组与对照组。对照组给予单纯的美托洛尔药物治疗;观察组给予美托洛尔+胺碘酮药物治疗,对比两组患者的临床疗效。结果经治疗,观察组患者的总有效率明显高于对照组,差异有统计学意义(P<0.05)。两组不良反应比较,差异有统计学意义(P<0.05)。结论给予老年房颤患者美托洛尔+胺碘酮药物治疗,能够取得良好的治疗效果,且安全性较高,值得推广。Objective To evaluate the clinical efficacy of metoprolol and amiodarone on elderly patients with atrial fibrillation in clinical practice and analyze its adverse reactions.Methods Fifty elderly patients with atrial fibrillation were enrolled and randomly divided into observation group and control group. The control group was given a simple combined medication metoprolol;observation group was treated with metoprolol+amiodarone medication. The clinical efficacy of the two groups were compared. Results After treatment, compared with control group, observation group had higher levels of total effective rate (P&lt;0.05). There was significant difference in adverse reactions between two groups (P&lt;0.05). Conclusion Treating elderly atrial fibrillation patients with metoprolol +amiodarone had a good therapeutic effect and safety.

关 键 词：胺碘酮 美托洛尔 老年房颤 窦律 疗效 不良反应 

分 类 号：R54[医药卫生—心血管疾病]