运动负荷试验在川崎病随访中的临床意义  

The clinical significance of exercise tolerance test in the follow-up of Kawasaki disease

作　　者：陈明[1] 谭晓林[2] 吴嘉荣[1] 黄峻[1] 覃杰华[1] 廖明超 刘玉玲[3] 张碧宏 

机构地区：[1]南方医科大学附属中山市博爱医院心电生理科,广东中山528403 [2]南方医科大学附属中山市博爱医院内科,广东中山528403 [3]南方医科大学附属中山市博爱医院儿科,广东中山528403 [4]南方医科大学附属中山市博爱医院心超室,广东中山528403

出　　处：《江苏实用心电学杂志》2013年第3期672-674,共3页Journal of Practical Electrocardiology JS

基　　金：广东省中山市科技局基金资助项目(20113A117)

摘　　要：目的探讨运动负荷试验在川崎病(Kawasaki disease,KD)随访中的临床意义。方法从本院2003年以来诊断为KD的100例患儿中筛选符合本次试验的54例,并根据超声心动图的结果分成两组,分别为冠状动脉损伤组24例和无冠状动脉损伤组30例,将两组运动负荷试验各项参数进行比较。结果 54例KD患儿中有26例出现运动负荷试验异常改变(48.2%),其中冠状动脉损伤组20例出现运动负荷试验异常(83.3%),无冠状动脉损伤组6例运动负荷试验异常(20%);而冠状动脉损伤组中以ST-T异常最多见,有16例(66.7%),其次为耐量下降(33.3%)、期前收缩(20.8%)。此3项参数(ST-T异常、耐量下降、期前收缩)与无冠状动脉损伤组比较,差异有统计学意义(P<0.05),其他参数两组比较,差异无统计学意义(P>0.05)。结论运动负荷试验用于KD患儿的随访与诊断,可重复多次检查,是一种安全可行的、用以评价冠状动脉病变的非侵入性检查方法。Objective To explore the clinical significance of exercise tolerance test(ETT)in the follow-up of Kawasaki disease(KD).Methods Among the 100 children diagnosed with KD in our hospital since 2003,select 54 cases who were suitable for the test and divide them into two groups according to the results of echocardiogram.There were 24 cases in coronary-artery-lesion group and 30 in non-coronary-artery-lesion group.Compare the parameters of EET in those two groups.Results Abnormal changes in ETT were detected in 26 out of 54 cases which accounted for 48.2%,and the coronary-artery-lesion group shared 20 cases(83.3%)while the other group 6 cases(20%).The majority of changes in the coronary-artery-lesion group represented as ST-T abnormality(16 cases,66.7%),followed by decrease of tolerance dose(33.3%)and premature beat(20.8%).Comparing the 3 parameters between the two groups,the difference was statistically significant(P&lt;0.05)while other parameters without statistical significance(P&gt;0.05).Conclusion The exercise tolerance test can be repeatable for the follow-up and diagnosis of KD patients which is one of the safe,feasible and non-invasive methods in evaluating coronary artery disease.

关 键 词：川崎病 运动负荷试验 冠状动脉损害 

分 类 号：R54[医药卫生—心血管疾病]