2-甲基-4,6-嘧啶二酮制备工艺的改进研究  

2-methyl-4,6-pyrimidine diketonepreparation technology of improvement research

作　　者：李文苗[1] 杜耀[1] 王志远[1] 周芙蓉[1] 

机构地区：[1]中北大学化工与环境学院,山西太原030051

出　　处：《化工中间体》2013年第11期42-45,共4页

摘　　要：研究了以盐酸乙脒和丙二酸二乙酯为原料,以甲醇钠为倦化剂制备1,1-二氨基-2,2-二硝基乙烯的中间体2-甲基-4,6-嘧啶二酮的方法。确定了最佳工艺条件,在该工艺条件下,2-甲基-4,6-嘧啶二酮的的得率达80%以上。与其他催化剂相比,采用甲醇钠作为催化荆,产品得率高,工艺条件温和,易于控制。The synthesis of intermediates 2-methyl-4,6-pyrimidine diketone with acetamidinium chloride and diethyl malonate as raw materials,Sodium methoxideas catalyst was studied.The optimum technological conditions were determined,and under the condition of the process,2-methyl-4,6-pyrimidine diketone yield above 80%.Compared with other catalysts,using sodium methoxide as catalyst,high product yield,mild process conditions and easy to control.

关 键 词：2-甲基-4 6-嘧啶二酮 催化剂 制备 

分 类 号：TQ564[化学工程—炸药化工]