二次肾移植后驼峰状尿量变化:附1例报告并文献复习  

Hump shape change of urine after second time kidney transplantation:1 case report and the literature review

作　　者：高建 姜伟 刘彦斌 裴向克 禹猛 杨其顺 

机构地区：[1]解放军北戴河281医院北京军区肾脏移植中心泌尿外科,河北秦皇岛066100

出　　处：《实用器官移植电子杂志》2013年第5期290-292,共3页Practical Journal of Organ Transplantation(Electronic Version)

摘　　要：目的探讨移植肾功能延迟恢复(DGF)的常见病因及其诊治方法。方法报告1例患者在肾移植术后出现持续时间长达2个月的驼峰状尿量变化,并对该病的相关文献进行复习,分析引起DGF的因素。结果该患者行同种异体肾移植术后尿量出现驼峰状变化,经给予静脉输入抗人T细胞猪免疫球蛋白,应用丹参川芎嗪注射液等药物改善循环,并规律血液透析治疗清除体内的炎症介质,维持水、电解质和酸碱平衡,预防感染和支持治疗后,患者尿量逐渐趋于稳定;波动于2 000mL左右,血肌酐稳定于130μmol/L左右后出院。结论充分认识DGF的常见病因有利于降低DGF的发生率,一旦发生应宜早期选择血液净化,辅助相应措施,绝大多数DGF可以恢复。Objective To explore a common cause of delayed graft function(DGF)and its diagnosis and treatment methods. Methods One patient after renal transplantation were reported,who experience hump shape change of urine up to 2 months,and the related literature of the disease were reviewed toanalyze the causes of DGF. Results The allograft kidney transplantation patient show a hump shape change of urine,and was treated by porcine immunoglobulin of anti-human T cells,and Danshen and Chuanqongqin injection improving micro circulation. Regular hemodialysis was performed to remove the body of inflammatory mediators,and water, electrolyte and acid-base balance were maintained,and infection prevention and support treatment were done. Patient was discharged as urine output was gradually stabilized about 2 000 mL,and serum creatine around 130 μmol/L. Conclusion Full awareness of the common causes of DGF is helpful to reduce the incidence of DGF. In case of occurrence,early blood purification and auxiliary measures should be performed,and most DGF can recover.

关 键 词：肾移植 驼峰状尿量变化 移植肾功能延迟恢复 

分 类 号：R699[医药卫生—泌尿科学]