乙肝肝移植术后生活质量影响因素调查的研究  

Factors influencing the quality of life in transplanted patients for HBV-related disease

作　　者：王颖[1] 林美雄[1] 刘红[1] 王旭[1] 

机构地区：[1]北京武警总医院器官移植研究所,北京100039

出　　处：《实用器官移植电子杂志》2014年第1期30-34,共5页Practical Journal of Organ Transplantation(Electronic Version)

基　　金：武警部队基金资助项目(WZ200532)

摘　　要：目的对移植受者进行随访教育,采取积极的干预措施,从而建立健康信念模式,减少不良健康事件的发生,并提高患者的长期存活率和生活质量。方法回顾性分析2006年1月至2009年1月中国肝脏移植注册系统(CLTR)记录并在武警总医院器官移植研究所随访接受调查的肝移植术后患者374例,所有患者均签署知情同意书,符合医学伦理学规定。将374例患者随机分为健康模式干预组(190例)和常规随访组(184例),健康模式干预组采取随访教育干预随访过程,常规随访组不予以健康教育干预,比较两组术后各主要不良事件的发生率。结果通过长期肝脏移植患者的追踪发现许多患者常常忽视术后随访,调查结果的统计分析发现,年龄大、受中等教育者术后更需要心理疏导,术后随访不当更容易出现心理问题、影响生活治疗。对本中心移植术后6个月患者进行随访干预后,与常规随访组比较,术后各主要不良事件的发生率差异均具有统计学意义(均P<0.05)。结论肝脏移植术后患者必须高度重视术后随访,按时服药。应用健康信念模式可降低不良事件的发生,提高患者长期生存率和生活质量。Objective To follow for education in transplant recipients,to take active interventions,so as to establish the health belief model to reduce the incidence of adverse health events and improve long-term survival and quality of life of patients. Methods CLTR records and follow-up examination of 374 patients transplanted for HBV-related disease who were admitted to the General Hospital of Chinese People's Armed Police Forces from January 2006 to January 2009 were analysed retrospectively. All participants in this study were given written informed consent and consistently in accord with ethical or legal standards. 374 patients were randomly divided into 190 cases of the health model intervention group and 184 cases the routine follow-up group. The health model intervention group was taken educational intervening during follow up. It was found that many patients often ignore the postoperative follow-up by long-term tracking of liver transplant patients. Results The statistical analysis of investigation results found that elder patients and secondary education need more psychological counseling than others. They were easier to psychological problems and affecting life treatment after improper postoperative follow-up. After the transplant center patients after 6 months of follow-up health model intervention compared with the control group,the major difference in the incidence of postoperative adverse events were statistically significant(all P<0.05). Conclusions Liver transplanted patients must attach great importance to the postoperative follow-up. The health belief model can reduce the patient's incidence of adverse events and improve their long-term survival rate and quality.

关 键 词：乙型病毒性肝炎 肝移植 随访 

分 类 号：R657.3[医药卫生—外科学]