糖尿病患者踝肱指数与代谢指标的关系  

Relationship between ankle-branchial index and cardiovascular risk factors in patients with type 2 diabetes

作　　者：王爱红[1] 许樟荣[1] 王玉珍[1] 史琳涛[1] 倪彩虹[1] 

机构地区：[1]解放军第306医院全军糖尿病诊治中心,北京市100101

出　　处：《总装备部医学学报》2007年第1期7-9,共3页Medical Journal of General Equipment Headquarters

基　　金：首都医学发展科研基金(2002-1013)

摘　　要：目的了解踝肱指数(ABI)在诊断2型糖尿病患者下肢动脉病变中的意义及其影响因素。方法采用多普勒血流探测仪测定糖尿病280例的足背动脉、胫后动脉与肱动脉的比值,ABI比值小于0.9为异常。结果本组病例中ABI<0.9者60例,占21.43%。糖尿病并发下肢动脉病变组与正常组比较,前者的年龄大、病程长、餐后血糖、甘油三酯、低密度脂蛋白胆固醇、尿白蛋白/肌酐比值的对数值、脉压差、吸烟率与并存冠心病率明显增高,舒张压和糖化血红蛋白(HbA1c)达标率明显降低。逐步回归分析显示,年龄、病程、甘油三酯、HbA1c是影响ABI的独立因素。结论ABI是一项分析下肢动脉病变的可靠指标,其花费小,且简单无创。增龄、病程长、高甘油三酯、高血糖是加剧下肢动脉硬化过程的主要因素。Objective To investigate the relationship between ankle-branchial index(ABI) and cardiovascular risk factors in patients with type 2 diabetes.Methods ABI was examined in the 280 patients with type 2 diabetes.All the patients were divided into group A(ABI≥0.9) and group B(ABI<0.9).The related risk factors of artherosclerosis were analyzed.Results 60 patients(21.43%) with abnormal ABI had older age(63.4±10.9 vs 53.3±11.3 yrs),longer duration(96.0±98.7 vs 37.8±53.4 months),higher 2 h post-meal blood glucose(15.85±4.80 vs 13.57±4.96) mmol/L,higher triglycerides(2.8±2.5 vs 2.1±1.6) mmol/L and LDL-cholesterol(3.1±0.8 vs 2.7±1.2) mmol/L,log-transferred urine albumin(1.40±0.50 vs 1.21±0.52),lower diastolic blood pressure(73.5±8.2 vs 78.4±11.0) mmHg and higher difference of systolic and diastolic blood pressure(60.5±16.6 vs 55.4±14.5) mmHg.There were lower percentage of the patients with HbA1c<7%(23.3% vs 40.5%),more smokers(51.7% vs 31.0%) and more patients with cardiovascular diseases(43.3% vs 22.2%) in group B than those in group A. Conclusions It is easy and with low cost to check ABI for diagnosing peripheral artery disease in diabetic patients.The patients with abnormal ABI have the more severe macrovascular risk factors.

关 键 词：2型糖尿病 踝肱指数 下肢动脉病变 

分 类 号：R587.1[医药卫生—内分泌]