胎儿期第五、六脑室扩张的围产儿结局随访  

Study about Expansion of Fetal Carum Septum Pellucidum and Carum Vergae

作　　者：陆铭娜[1] 贺晶[1] 蔡淑萍[1] 

机构地区：[1]浙江大学医学院附属妇产科医院,浙江杭州310006

出　　处：《中国产前诊断杂志（电子版）》2009年第2期19-23,共5页Chinese Journal of Prenatal Diagnosis(Electronic Version)

基　　金：浙江省医学重点建设学科(产科学07-008)项目资助

摘　　要：目的探讨产前超声发现胎儿脑中线部位第五、六脑室扩张的临床意义。方法2006年1月至2008年12月在本院产前超声检查发现胎儿第五、六脑室扩张者纳入研究对象并定期超声随访并记录围产儿结局直至妊娠终止或出生后1年。结果共发现胎儿第五、六脑室扩张病例58例,发生率为0.19%,其中7例最终失访。发现扩张的孕周为妊娠24～37周,平均30±4周;有24例(24/51,47.0%)妊娠期随访中扩张程度减少,其中完全恢复正常19例,最终围产儿结局良好;妊娠期胎儿第五、六脑室扩张程度减少与否,其围产儿结局有统计学差异(P<0.05)。单纯第五、六脑室扩张,无合并其他异常者与合并其他异常者相比,其围产儿不良结局有统计学差异(60.8%,39.2%,P<0.05)。结论胎儿第五、六脑室扩张主要发生在孕中晚期,定期B超随访发现扩张程度减少者围产儿预后多良好。胎儿第五、六脑室扩张合并其他脏器异常则常提示围产儿结局不良。Objective To discuss the clinical significance of fetal large cavum septum pellucidum and cavum vergae by prenatal ultrasonography. Methods Prenatal ultrasonography was performed on women at our hospital for prenatal diagnosis during January 2006 to December 2008. The changes of fetal large cavum septum pellucidum and cavum vergae were observed regularly until delivery.The live infants were followed up regularly in one year. Results Totally 58 women with fetal large cavum septum pellucidum and cavum vergae were included in the study,with the incidence of 0.19%.But 7 cases losed in the observating progress. They were diagnosed between 24~37 gestational weeks,with a median of (30±4) weeks. In the pregnancy period,24 cases (24/51,47.0%) of the large cavum septum pellucidum and cavum vergae were decreased,and 19 cases were seen decreased to nomal degree in gestation. There was significant difference between the two groups,which the degree of cavum septum pellucidum and cavum vergae expansion decreased and the other didn’t,also with statistical significance (P<0.05). And between cases which were combined with other abnormalities with large cavum septum pellucidum and cavum vergae and the others not,perinatal outcomes also have significant difference (P<0.05).Conclusion Fetus with large cavum septum pellucidum and cavum vergae occur mainly in the second and third trimesters of pregnancy. When we found that the degree of the expansion degree of fetal large cavum septum pellucidum and cavum vergae decreased,it may be possible good signs of perinatal outcomes. Either it is combined with other intracranial and extracranial structures anomalies can affect the perinatal outcomes. So when the ultrasound examination diagnosis of large cavum septum pellucidum and cavum vergae,we should be close ultrasound follow-up of the size of cavum septum pellucidum and cavum vergae and other intracranial,extracranial structures anomalies.

关 键 词：超声检查 胎儿 第五脑室 第六脑室 

分 类 号：R714.7[医药卫生—妇产科学]