经小隐静脉置管溶栓治疗下肢深静脉血栓形成  

Catheter-directed thrombolysis via small saphenous vein for deep venous thrombosis of lower limb

作　　者：萧剑彬[1] 林少芒[1] 张智辉[1] 李强[1] 刘金玲[1] 吴权辉[1] 

机构地区：[1]广州医学院第二附属医院血管外科,广州510260

出　　处：《中国血管外科杂志（电子版）》2012年第1期26-28,共3页Chinese Journal of Vascular Surgery(Electronic Version)

摘　　要：目的评价小隐静脉置管溶栓治疗下肢深静脉血栓形成(DVT)的临床疗效。方法 25例急性下肢DVT患者,经小隐静脉溶栓导管直接插入静脉血栓,微泵推注尿激酶(168.45±82.34)万U溶栓。以术前、后的健、患肢周径差及静脉通畅度评价疗效。结果置管溶栓治疗后,膝上周径减少[(4.9±0.8)cmvs(1.4±0.5)cm,P<0.01);膝下周径减少[(3.8±0.6)cmvs(1.0±0.4)cm,P<0.01]。术前、后静脉通畅度评分显著改善(7.6±1.5vs1.8±0.7,P<0.01)。治疗过程中无严重并发症。结论经小隐静脉置管溶栓治疗下肢DVT是一种安全高效的治疗方法。Objective To evaluate the efficacy of catheter-directed thrombolysis(CDT) via small saphenous vein(SSV) for deep venous thrombosis (DVT) of lower limb. Methods Twenty-five patients with DVT of lower limbs underwent CDT via SSV, with continuous infusion of urokinase [(168.45±82.34)×104 U]. The circumferences and the venous patency were observed before and after the thrombolysis. Results The circumferences of lower limb were significantly different [above the knee:(4.9±0.8)cm vs (1.4±0.5)cm,P<0.01; below the knee: (3.8±0.6) cm vs (1.0±0.4) cm,P<0.01] before and after the procedure. The venous patency score has significantly improved (7.6±1.5 vs 1.8±0.7,P<0.01)without severe complications. Conclusion CDT via SSV for DVT of lower limb is safe and effective.

关 键 词：深静脉血栓形成 小隐静脉 置管溶栓 消肿百分比 溶栓百分比 

分 类 号：R543.6[医药卫生—心血管疾病]