噬血细胞综合征诊断分析  

Diagnostic analysis on Henophagocytic Syndrome

作　　者：崔娟红[1] 赵怡雯[1] 杨晓莉[1] 郝钦芳[1] 王秀梅[1] 姚桂玲[1] 宋丽洁[1] 

机构地区：[1]中国人民武装警察部队总医院检验科,北京100039

出　　处：《临床检验杂志（电子版）》2012年第4期252-254,共3页Clinical Laboratory Journal(Electronic Edition)

摘　　要：目的分析嗜血细胞综合征(HPS)患者的临床特点,提高对本病的早期诊断、早期治疗。方法对8例患者的临床资料及实验室资料进行回顾性分析。结果 5例小儿EBV感染阳性,1例CMV阳性,1例为莱姆病,1例为细菌感染;临床以发热、肝脾淋巴结肿大为突出表现,实验室检查有不同程度肝功能损害、血清铁蛋白增高、全血细胞减少、凝血功能障碍,骨髓内均可见到吞噬血细胞的组织细胞。结论 HPS可由多种病因所致,临床表现多样、病死率高,应及时行骨髓穿刺,以减少误诊和漏诊。Objective To improve early diagnosis and therapy by analysis of the clinical features of Henophagocytic Syndrome.Methods 8 cases of clinical manifestations and laboratory parameters were retrospectively analyzed.Results 5 cases of EBV infection positive.1 case accompany CMV positive,1 case accompany Borrelia burgdorferi,1 case infected by bacterial.The main clinical manifestations including fever,swelling of liver,spleen and lymph nodes.Laboratory findings included different degree liver function damage,pancytopenia,disturbance of blood coagulation,phagocytic tissue cells in the bone marrow.Conclusion HPS may be caused by Many diseases.It characterized by multifarious clinical feature,high case fatality rate.Bone marrow puncture can reduce the misdiagnoses and missed diagnoses.

关 键 词：嗜血细胞综合征 临床特点 诊断 预后 

分 类 号：R55[医药卫生—血液循环系统疾病]