New insights in diabetic foot infection  

作　　者：Jean-Louis Richard Albert Sotto Jean-Philippe Lavigne 

机构地区：[1]Department of Nutritional Diseases and Diabetology,Medical Centre,University Hospital of Nmes,Le Grau du Roi 30240,France [2]Department of Infectious Diseases,Carémeau Hospital,University Hospital of Nmes,30029 Nmes and INS- ERM,ERI 26,UFR de Médecine,30908 Nmes Cedex 02, France [3]Laboratory of Bacteriology,Carémeau Hospital,University Hospital of Nmes,30029 Nmes,France and INSERM,ERI 26,UFR de Médecine,30908 Nmes Cedex 02,France

出　　处：《World Journal of Diabetes》2011年第2期24-32,共9页世界糖尿病杂志（英文版）（电子版）

基　　金：Supported by Institut National de la SantéEt de la Recherche Médicale,the French Speaking Association for Diabetes and Metabolic Diseases(ALFEDIAM grant);the University of Montpellier 1,the Languedoc-Roussillon Area(Chercheur d'avenir Grant) and the City of Nmes

摘　　要：Foot ulcers are common in diabetic patients,have a cumulative lifetime incidence rate as high as 25%and frequently become infected.The spread of infection to soft tissue and bone is a major causal factor for lowerlimb amputation.For this reason,early diagnosis and appropriate treatment are essential,including treatment which is both local(of the foot)and systemic(metabolic),and this requires coordination by a multidisciplinary team.Optimal treatment also often involves extensive surgical debridement and management of the wound base,effective antibiotic therapy,consideration for revascularization and correction of metabolic abnormalities such as hyperglycemia.This article focuses on diagnosis and management of diabetic foot infections in the light of recently published data in order to help clinicians in identification,assessment and antibiotic therapy of diabetic foot infections.Foot ulcers are common in diabetic patients, have a cumulative lifetime incidence rate as high as 25% and frequently become infected. The spread of infection to soft tissue and bone is a major causal factor for lower-limb amputation. For this reason, early diagnosis and appropriate treatment are essential, including treatment which is both local (of the foot) and systemic (metabolic), and this requires coordination by a multidisciplinary team. Optimal treatment also often involves extensive surgical debridement and management of the wound base, effective antibiotic therapy, consideration for revascularization and correction of metabolic abnormalities such as hyperglycemia. This article focuses on diagnosis and management of diabetic foot infections in the light of recently published data in order to help clinicians in identification, assessment and antibiotic therapy of diabetic foot infections.

关 键 词：DIABETIC FOOT ULCER INFECTION MANAGEMENT 

分 类 号：R587.2[医药卫生—内分泌]