Myxedema ascites with high CA-125:Case and a review of literature  

作　　者：Bou Khalil Roula El Rassi Patrick Chammas Nizar Obeid Jean Ghabach Maroun Sakr Charles Itani Tarek Farhat Said 

机构地区：[1]Quarantaine Governmental University Medical Hospital,Beirut 961,Lebanon [2]Saint Georges University Medical Center,University of Balamand,Beirut 961,Lebanon [3]Department of Surgery,Lebanese University,Beirut 961,Lebanon [4]Chairman of Anesthesia Department,Rosary Hospital,Beirut 961,Lebanon

出　　处：《World Journal of Hepatology》2013年第2期86-89,共4页世界肝病学杂志（英文版）（电子版）

摘　　要：Ascites appearing in a previously healthy female patient is usually ascribed to a variety of causes,among which,is a cancerous process,especially if it comes with a raised CA-125 level.Although the CA-125 antigen is present on more than 80% of malignant epithelial ovarian tissue of non-mucinous type,it is also found on both healthy and malignant cells of mesothelial and non-mesothelial origin.Myxedema ascites which is caused by hypothyroidism is a rare entity,but on the other hand is easy to treat.It is one of the differential diagnoses when the ascites is refractory to treatment and no other obvious cause can be identified.If the diagnosis is delayed,patients will frequently receive unnecessary procedures,while treatment has very good response rates and ascites resolve with serum CA-125 normalization after adequate hormonal treatment.Ascites appearing in a previously healthy female patient is usually ascribed to a variety of causes,among which,is a cancerous process,especially if it comes with a raised CA-125 level.Although the CA-125 antigen is present on more than 80% of malignant epithelial ovarian tissue of non-mucinous type,it is also found on both healthy and malignant cells of mesothelial and non-mesothelial origin.Myxedema ascites which is caused by hypothyroidism is a rare entity,but on the other hand is easy to treat.It is one of the differential diagnoses when the ascites is refractory to treatment and no other obvious cause can be identified.If the diagnosis is delayed,patients will frequently receive unnecessary procedures,while treatment has very good response rates and ascites resolve with serum CA-125 normalization after adequate hormonal treatment.

关 键 词：HYPOTHYROIDISM Refractory ASCITES HIGH CA-125 Hormonal therapy Abdominal PARACENTESIS 

分 类 号：R581.2[医药卫生—内分泌]