Peritonitis in myelofibrosis:a cautionary tale  

作　　者：Narasimhaiah Srinivasaiah Mohammad K Zia Vummiti Muralikrishnan 

机构地区：[1]Department of General Surgery,Princess of Wales Hospital

出　　处：《Hepatobiliary & Pancreatic Diseases International》2010年第6期651-653,共3页国际肝胆胰疾病杂志（英文版）

摘　　要：BACKGROUND: Primary myelofibrosis (PMF) is a myeloproliferative disorder characterized by bone marrow fibrosis. Extra-medullary hematopoiesis sometimes occurs even in the peritoneal cavity, apart from organs such as the liver, spleen, and lymph nodes. This may sometimes be complicated by spontaneous infection and complications. We report a rather unusual case of PMF, who presented as an emergency with spontaneous peritonitis to general surgery department and had a fulminant clinical course. METHOD: A clinical case note review was done and a literature search was undertaken. RESULTS: A rather unusual case of PMF, who presented as an emergency with spontaneous peritonitis to general surgery department. The patient underwent a laparotomy and had a fulminant clinical course. CONCLUSIONS: Peritonitis in myelofibrosis may have a number of causes. Clinicians need to be aware of them and provide conservative management prior to surgical treatment. (Hepatobiliary Pancreat Dis Int 2010; 9: 651-653)BACKGROUND: Primary myelofibrosis (PMF) is a myeloproliferative disorder characterized by bone marrow fibrosis. Extra-medullary hematopoiesis sometimes occurs even in the peritoneal cavity, apart from organs such as the liver, spleen, and lymph nodes. This may sometimes be complicated by spontaneous infection and complications. We report a rather unusual case of PMF, who presented as an emergency with spontaneous peritonitis to general surgery department and had a fulminant clinical course. METHOD: A clinical case note review was done and a literature search was undertaken. RESULTS: A rather unusual case of PMF, who presented as an emergency with spontaneous peritonitis to general surgery department. The patient underwent a laparotomy and had a fulminant clinical course. CONCLUSIONS: Peritonitis in myelofibrosis may have a number of causes. Clinicians need to be aware of them and provide conservative management prior to surgical treatment. (Hepatobiliary Pancreat Dis Int 2010; 9: 651-653)

关 键 词：primary myelofibrosis hepato-splenomegaly splenic rupture extra-medullary hematopoiesis sepsis PERITONITIS 

分 类 号：R656.4[医药卫生—外科学]