Antimicrobial properties of Teucrium polium against some clinical pathogens  

作　　者：Esmaeil Darabpour Hossein Motamedi Seyyed Mansour Seyyed Nejad 

机构地区：[1]Department of Biology,Faculty of Science,Shahid Chamran University

出　　处：《Asian Pacific Journal of Tropical Medicine》2010年第2期124-127,共4页亚太热带医药杂志（英文版）

摘　　要：Objective:To explore the antibacterial effect of the alcoholic extracts of aerial parts of Teucrium polium,native in Iran on some pathogenic bacteria.Methods:Antibacterial activity of ethanolic extract(50 to 400 mg/mL) and methanolic extract(400 and 600 mg/mL) was evaluated by disc diffusion method.Results:The ethanolic extract results showed that Bacillus anthracis was the most sensitive species,while Escherichia coli and Proteus mirabilis were more resistant than others.In the case of the methanolic extract,Bordetella bronchiseptica was the most sensitive and Proteus mirabilis and Arcanobacterium pyogenes were the most resistant species.The hydroalcoholic extract of Teucrium polium had a relatively satisfactory effect on Salmonella typhi. The minimal inhibitory concentration(MIC) of Staphylococcus aureus and Salmonella typhi was 40 mg/mL and Bordetella bronchiseptica and Bacillus anthracis was 10 mg/mL.The minimal bactericidal concentration(MBC) against Bacillus anthracis was 10 mg/mL while against other species were not found(】200 mg/mL).The methanolic extract had also synergistic effect with methicillin,vancomycin against Staphylococcus aureus and with novobiocin against Salmonella typhi.Conclusions:These results suggest that this plant contains relatively good antibacterial activity and it can be used as a source of antiseptic compounds for medicinal uses.Objective:To explore the antibacterial effect of the alcoholic extracts of aerial parts of Teucrium polium,native in Iran on some pathogenic bacteria.Methods:Antibacterial activity of ethanolic extract(50 to 400 mg/mL) and methanolic extract(400 and 600 mg/mL) was evaluated by disc diffusion method.Results:The ethanolic extract results showed that Bacillus anthracis was the most sensitive species,while Escherichia coli and Proteus mirabilis were more resistant than others.In the case of the methanolic extract,Bordetella bronchiseptica was the most sensitive and Proteus mirabilis and Arcanobacterium pyogenes were the most resistant species.The hydroalcoholic extract of Teucrium polium had a relatively satisfactory effect on Salmonella typhi. The minimal inhibitory concentration(MIC) of Staphylococcus aureus and Salmonella typhi was 40 mg/mL and Bordetella bronchiseptica and Bacillus anthracis was 10 mg/mL.The minimal bactericidal concentration(MBC) against Bacillus anthracis was 10 mg/mL while against other species were not found(>200 mg/mL).The methanolic extract had also synergistic effect with methicillin,vancomycin against Staphylococcus aureus and with novobiocin against Salmonella typhi.Conclusions:These results suggest that this plant contains relatively good antibacterial activity and it can be used as a source of antiseptic compounds for medicinal uses.

关 键 词：TEUCRIUM polium Antibiotic HERBAL MEDICINE 

分 类 号：R285[医药卫生—中药学]