Anti-Toxocara spp.antibodies in an adult healthy population:serosurvey and risk factors in Southeast Brazil  

作　　者：Elaine Cristina Negri Vamilton Alvares Santarem Guita Rubinsky-Elefant Rogerio Giuffrida 

机构地区：[1]Post Graduation in Animal Science Master Program/Universidade do Oeste Paulista[Unoeste],Pro-Reitoria de Pesquisa e Pos-Graduacao,Rod.Raposo Tavares km 572,Bairro Limoeiro,19067-175 Presidente Prudente,Sao Paulo,Brazil [2]Laboratory of Preventive Veterinary Medicine,Veterinary Teaching-Hospital-Unoeste-Rod.Raposo Tavares km 572,Bairro Linmeiro,19067-175 Presidente Prudente,Sao Paulo.Brazil [3]Laboratory of Seroepidemiology and Immunobiology-Instituto de Medicina Tropical de Sao Paulo-University of Sao Paulo,Av Dr Eneas deCarralho Aguiar 470,05403-000 Sao Paulo,SP,Brazil [4]Laboratory of Preventive Veterinary Medicine,Veterinary Teaching-Hospital-Unoeste-Rod.Raposo Tavares km 572,Bairro Linmeiro,19067-175Presidente Prudente,Sao Paulo.Brazil

出　　处：《Asian Pacific Journal of Tropical Biomedicine》2013年第3期211-216,共6页亚太热带生物医学杂志（英文版）

基　　金：Supported by Universidade do Oeste Paulista (Unoeste)(Grant No.184/2009)

摘　　要：Objective:To evaluate the frequency of anti-Toxocara spp.antibodies in an adult healthy population.Methods:The study was performed by interviewing 253 blood donors,from 19 to65 years of age,in a hematological centre in Presidente Prudente,S(?)o Paulo,southeast Brazil.A survey was applied to blood donors in order to evaluate the possible factors associated to the presence of antibodies,including individual(gender and age),socioeconomic(scholarship,familial income and sanitary facilities)and habit information(contact with soil,geophagy,onycophagy and intake of raw/undercooked meat)as well as the presence of dogs or cats in the household.ELISA test was run for detection of the anti-Toxocara spp.IgG antibodies.Bivariate analysis followed by logistic regression was performed to evaluate the potential risk factors associated to seropositivity.Results:The overall prevalence observed in this study was 8.7%(22/253).Contact with soil was the unique risk factor associated with the presence of antibodies(P=0.0178;0R=3.52;95%CI=1.244-9.995).Conclusions:The results of this study reinforce the necessity in promoting preventive public health measures,even for healthy adult individual,particularly those related to the deworming of pets to avoid the soil contamination,and hygiene education of the population.Objective:To evaluate the frequency of anti-Toxocara spp.antibodies in an adult healthy population.Methods:The study was performed by interviewing 253 blood donors,from 19 to65 years of age,in a hematological centre in Presidente Prudente,S(?)o Paulo,southeast Brazil.A survey was applied to blood donors in order to evaluate the possible factors associated to the presence of antibodies,including individual(gender and age),socioeconomic(scholarship,familial income and sanitary facilities)and habit information(contact with soil,geophagy,onycophagy and intake of raw/undercooked meat)as well as the presence of dogs or cats in the household.ELISA test was run for detection of the anti-Toxocara spp.IgG antibodies.Bivariate analysis followed by logistic regression was performed to evaluate the potential risk factors associated to seropositivity.Results:The overall prevalence observed in this study was 8.7%(22/253).Contact with soil was the unique risk factor associated with the presence of antibodies(P=0.0178;0R=3.52;95%CI=1.244-9.995).Conclusions:The results of this study reinforce the necessity in promoting preventive public health measures,even for healthy adult individual,particularly those related to the deworming of pets to avoid the soil contamination,and hygiene education of the population.

关 键 词：TOXOCARIASIS Larva migrans SEROPREVALENCE Diagnostic Epidemiology 

分 类 号：R195[医药卫生—卫生统计学]