Tegumental histological effects of Mirazid~ and myrrh volatile oil on adult Fasciola gigantica  

作　　者：Ahmad Mohamed Massoud Hatem Abdel Mawgoud Shalaby Rabab Mohamed El Khateeb Mona Said Mahmoud Mohamed Abdel Aziz Kutkat 

机构地区：[1]Tropical Medicine Department,Faculty of Medicine,Al-Azhar University [2]Parasitology and Animal Diseases Department,National Research Center [3]Poultry Diseases Department,National Research Center

出　　处：《Asian Pacific Journal of Tropical Biomedicine》2013年第6期501-504,共4页亚太热带生物医学杂志（英文版）

基　　金：Supported by National Research Center,Egypt,through the Parasitology and Animal Diseases Department(Grant No.9040203)

摘　　要：Objective:To evaluated the histological changes within the tegument of adult Fasciola gigantica(F.gigantica)that led to the gross changes that were visible externally.Methods:The effects of oleoresin extract of myrrh(Mirazid^(?)),myrrh volatile oil and triclabendazole sulphoxide(reference drug)on the tegumental structure of adult F.gigantiea following treatment in vitro had been determined by light microscopy.Results:The internal changes in the tegument observed in this study were compatible with surface changes seen in the previous scanning electron microscopy study,using the same drugs.The swelling of tegumental syncytium was a particular feature of their action,but its level was much greater with myrrh volatile oil,in which vacuolization of the tegument and loss of spines were observed.Conclusions:The present study demonstrated the fasciocidal properties of Mirazid^(?)oleoresin extract,and it might be possible to reinforce its fasciocidal activity by increasing its content of myrrh volatile oil.Objective:To evaluated the histological changes within the tegument of adult Fasciola gigantica（F.gigantica）that led to the gross changes that were visible externally.Methods:The effects of oleoresin extract of myrrh(Mirazid?),myrrh volatile oil and triclabendazole sulphoxide（reference drug）on the tegumental structure of adult F.gigantiea following treatment in vitro had been determined by light microscopy.Results:The internal changes in the tegument observed in this study were compatible with surface changes seen in the previous scanning electron microscopy study,using the same drugs.The swelling of tegumental syncytium was a particular feature of their action,but its level was much greater with myrrh volatile oil,in which vacuolization of the tegument and loss of spines were observed.Conclusions:The present study demonstrated the fasciocidal properties of Mirazid?oleoresin extract,and it might be possible to reinforce its fasciocidal activity by increasing its content of myrrh volatile oil.

关 键 词：FASCIOLA gigantica Mirazid Myrrh VOLATILE OIL HISTOLOGICAL effect 

分 类 号：S852.7[农业科学—基础兽医学]