In vitro antimicrobial activity of mangrove plant Sonneratia alba  

作　　者：Shahbudin Saad Muhammad Taher Deny Susanti Haitham Qaralleh Anis Fadhlina Izyani Bt Awang 

机构地区：[1]Institute of Oceanography and Maritime Studies, Kulliyyah of Science, International Islamic University Malaysia,Jalan Sultan Ahmad Shah,Bandar Indera Mahkota,25200 Kuantan, Pahang, Malaysia [2]Department of Pharmaceutical Technology, Faculty of Pharmacy, International Islamic University Malaysia,Jalan Sultan Ahmad Shah,25200Kuantan, Pahang, Malaysia [3]Department of Biomedical Science, Faculty of Science, International Islamic University Malaysia,Jalan Sultan Ahmad Shah,25200 Kuantan,Pahang, Malaysia

出　　处：《Asian Pacific Journal of Tropical Biomedicine》2012年第6期427-429,共3页亚太热带生物医学杂志（英文版）

基　　金：financially supported by Faculty of Science,International Islamic University Malaysia

摘　　要：Objective:To investigate the antimicrobial property of mangrove plantSonneratia alba(S. alba).Methods:The antimicrobial activity was evaluated using disc diffusion and microdilution methods against six microorganisms. Soxhlet apparatus was used for extraction with a series of solvents,n-hexane, ethyl acetate and methanol in sequence of increasing polarity.Results:Methanol extract appeared to be the most effective extract whilen-hexane extract showed no activity. The antimicrobial activities were observed against the gram positive bacteria Staphylococcus aureus(S. aureus) and Bacillus cereus(B. cereus), the gram negative Escherichia coli(E. coli) and the yeast Cryptococcus neoformans. Pseudomonas aeruginosa and Candida albicans appeared to be not sensitive to the concentrations tested since no inhibition zone was observed.E. coli(17.5 mm) appeared to be the most sensitive strain followed by S. aureus(12.5 mm)and B. cereus(12.5 mm).Conclusions:From this study, it can be concluded that S. alba exhibit santim icrobial activities against certain microorganisms.Objective:To investigate the antimicrobial property of mangrove plantSonneratia alba(S. alba).Methods:The antimicrobial activity was evaluated using disc diffusion and microdilution methods against six microorganisms. Soxhlet apparatus was used for extraction with a series of solvents,n-hexane, ethyl acetate and methanol in sequence of increasing polarity.Results:Methanol extract appeared to be the most effective extract whilen-hexane extract showed no activity. The antimicrobial activities were observed against the gram positive bacteria Staphylococcus aureus(S. aureus) and Bacillus cereus(B. cereus), the gram negative Escherichia coli(E. coli) and the yeast Cryptococcus neoformans. Pseudomonas aeruginosa and Candida albicans appeared to be not sensitive to the concentrations tested since no inhibition zone was observed.E. coli(17.5 mm) appeared to be the most sensitive strain followed by S. aureus(12.5 mm)and B. cereus(12.5 mm).Conclusions:From this study, it can be concluded that S. alba exhibit santim icrobial activities against certain microorganisms.

关 键 词：ANTIBACTERIAL ANTIFUNGAL SONNERATIA ALBA MANGROVES ANTIMICROBIAL activity 

分 类 号：R96[医药卫生—药理学]