变应性鼻炎患儿血清IL-13和特异性IgE水平测定  

Determination of serum IL-13 and IgE in children with allergic rhinitis

作　　者：纪丽莉[1] 原萍萍[1] 候晓锋[1] 贺云霞[2] 

机构地区：[1]山东省莱州市人民医院儿科,261400 [2]山东省莱州市人民医院耳鼻喉科,261400

出　　处：《中国现代药物应用》2007年第5期4-5,共2页Chinese Journal of Modern Drug Application

摘　　要：目的探讨变应性鼻炎患儿血清IL-13和sIgE水平变化及意义。方法采用ELISA法检测21例变应性鼻炎患儿、23例正常对照血清IL-13和SIgE水平。结果变应性鼻炎组血清IL-13及SIgE水平均高于对照组(P<0.01)。结论IL-13在变应性鼻炎发病中起一定作用,检测血清IL-13和SIgE水平对病情发展及转归的监测具有一定意义。Objective To explore variances and significances of serum IL-13 and SIgE in children with allergic rhinitis.Methods Serum IL-13,and SIgE were measured in 21 cases of allergic rhinitis and 23 cases of normal contro1 using ELISA.Results The serum IL-13and SIgE concentrations in allergic rhinitis group were significantly higher than those of normal control group(P<0.001).Conclusion IL-13 may play some role in the pathogenesis of allergic rhinitis.Determinating the serum IL-13 and SIgE is useful for monitoring the development and remission of allergic rhinitis.

关 键 词：变应性鼻炎 白细胞介素-13 IGE 儿童 

分 类 号：R765.21[医药卫生—耳鼻咽喉科]