阿昔洛韦联合干扰素治疗带状疱疹疗效观察  

Clinical Observation of Herpes Zoster Treated with Acyclovir and Interferon α-2b

作　　者：王冬梅[1] 李江涛[2] 

机构地区：[1]四川省宜宾市第一人民医院皮肤科,四川宜宾644000 [2]四川省宜宾市第一人民医院风湿内科,四川宜宾644000

出　　处：《中国医学文摘（皮肤科学）》2009年第2期69-70,共2页China Medical Abstracts(Dermatology)

摘　　要：目的探讨阿昔洛韦联合干扰素治疗带状疱疹的疗效。方法将120例患者随机分为两组,治疗组静滴阿昔洛韦5mg/(kg.次),3次/d,重组干扰素α-2b30μg和维生素B1100mg肌注,均1次/d;对照组除不用干扰素外,余同治疗组。结果两组在水疱结痂、止痛、痊愈时间上差异有统计学意义(P<0.05),两组有效率比较差异有统计学意义(P<0.05)。结论阿昔洛韦联合干扰素治疗带状疱疹起效快,疗程短,疗效好。Objective To observe the effect of herpes zoster treated with acyclovir and interferon. Methods 120 patients affected with herpes zoste were randomly divided into two groups. Among them, 60 patients given acyclovir (5 mg/kg,per times, Tid, ivgtt) and interferon-a2b (30 μg, per day, im) were as observed group, and the others treated with acyclovir (5 mg/kg, per times, Tid, ivgtt) only were as control group. Results Compared to the control group, patients treated with acyclovir and interferon showed shorter time of scab forming, pain relieving and recovery (P<0.05). The effective rate of two groups had significant difference (P<0.05). Conclusions The treatment on patients with herpes zoster with acyclovir and interferon is a useful, effective and safe therapy and could shorten course of treatment effect and decrease neuralgia.

关 键 词：带状疱疹 阿昔洛韦 重组干扰素Α-2B 治疗 

分 类 号：R752.12[医药卫生—皮肤病学与性病学]