妊高征孕妇在椎管内神经阻滞下血浆一氧化氮和内皮素水平的变化及其临床意义  

The variation of plasma nitric oxide and endothelin in patients with pregnancy induced hypertension with intra-vertebral canal nerve block and the dinkal value

作　　者：高丽君[1] 沈虹春[1] 戎小萍[1] 

机构地区：[1]慈溪市妇幼保健院,浙江慈溪315300

出　　处：《浙江医学教育》2009年第2期44-46,共3页Zhejiang Medical Education

摘　　要：目的:比较妊高征孕妇在硬膜外阻滞和蛛网膜下腔阻滞下一氧化氮(NO)和内皮素(ET)的变化。方法:选择30例中度妊高征行剖宫产患者,分别进行硬膜外阻滞(15例)和蛛网膜下腔阻滞(15例),并分别于阻滞前、胎儿娩出前、胎儿娩出后、胎盘娩出后抽取母体静脉血测定血浆NO和ET的浓度。结果:硬膜外阻滞组母体血液NO浓度高于蛛网膜下腔组,ET浓度两组比较无明显差别。结论:硬膜外阻滞较蛛网膜下腔阻滞更适宜用于妊高征孕妇的剖宫产手术。[Objective]The purpose of this study is to investigate the effects of epidural block and subarachnoid block on plasma nitrous oxide(NO) and endothelin level in patients with pregnancy - induced hypotension(PTH).[Method]30 patients with moderate pregnancy - induced hypertension gravies(FTH) undergoing Cesarean section were divided into EB team for epidural block and SB team for subarachnoid block.The intravenous blood samples were taken immediately before the block,before and after fetal delivery,after placenta expulsion completely to determine the plasma concentration of NO and ET.[Result]The plasma concentration of NO in maternal blood in EB team was higher than in SB team,but no significant difference was found between the two groups in the plasma concentration of EB.[Conclusion]Epidural block is probably more appropriate than subarachnoid block in the anesthetic methods for Caesarean Section in patients with pregnancy - induced hypotension(PIH).

关 键 词：妊高征 一氧化氮 内皮素 硬膜外阻滞 蛛网膜下腔阻滞 

分 类 号：R714.246[医药卫生—妇产科学]